A meta-analysis of bias at baseline in RCTs of attention bias modification: No evidence for dot-probe bias towards threat in clinical anxiety and PTSD.

Journal of Abnormal Psychology
Anne-Wil KruijtElaine Fox

Abstract

Considerable effort and funding have been spent on developing Attention Bias Modification (ABM) as a treatment for anxiety disorders, theorized to exert therapeutic effects through reduction of a tendency to orient attention toward threat. However, meta-analytical evidence that clinical anxiety is characterized by threat-related attention bias is thin. The largest meta-analysis to date included dot-probe data for n = 337 clinically anxious individuals. Baseline measures of biased attention obtained in ABM RCTs form an additional body of data that has not previously been meta-analyzed. This article presents a meta-analysis of threat-related dot-probe bias measured at baseline for 1,005 clinically anxious individuals enrolled in 13 ABM RCTs. Random-effects meta-analysis indicated no evidence that the mean bias index (BI) differed from zero (k = 13, n = 1005, mean BI = 1.8 ms, SE = 1.26 ms, p = .144, 95% confidence interval [-0.6, 4.3]. Additional Bayes factor analyses also supported the point-zero hypothesis (BF10 = .23), whereas interval-based analysis indicated that mean bias in clinical anxiety is unlikely to extend beyond the 0 to 5 ms interval. Findings are discussed with respect to strengths (relatively large samples, possi...Continue Reading

Citations

Nov 24, 2020·Frontiers in Psychology·Ondřej NovákKateřina Klapilová
Dec 23, 2020·Behavioral Sciences·Suzannah StuijfzandHelen Dodd
May 20, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Matthias J Wieser, Andreas Keil
Feb 23, 2021·Behaviour Research and Therapy·David YapTracy A Dennis-Tiwary
Mar 25, 2021·Clinical Psychological Science : a Journal of the Association for Psychological Science·Rebecca B PriceGreg J Siegle
Aug 21, 2021·Clinical Psychological Science : a Journal of the Association for Psychological Science·Andrea N NilesAoife O'Donovan
Oct 16, 2021·Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD)·Michiyo HiraiGeorge A Clum

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