A meta-analysis of induction therapy for advanced thymic epithelial tumors

The Annals of Thoracic Surgery
Masatsugu HamajiBryan M Burt

Abstract

This meta-analysis was designed to determine the effect of induction therapy and surgical resection on overall survival in patients with advanced thymic epithelial tumors. PubMed and Scopus databases were queried, and 12 studies comprising 266 patients were analyzed. Meta-analysis using a random effect model revealed a pooled rate of response to induction therapy of 59%, a pooled rate of complete resection of 73%, and pooled 5-year and 10-year overall survival of 87% and 76% after induction therapy, respectively. Surgical resection after induction therapy for advanced thymic epithelial tumors can be undertaken with favorable outcomes.

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Citations

Feb 24, 2016·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Giuseppe CardilloFilippo Lococo
Jan 17, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Enrico RuffiniPierre-Emmanuel Falcoz
Dec 11, 2020·Indian Journal of Surgical Oncology·Arvind KumarSukhram Bishnoi
Dec 8, 2020·Indian Journal of Surgical Oncology·Arvind KumarSrinivas Kodaganur Gopinath
Dec 11, 2020·Indian Journal of Surgical Oncology·Anvesh DharanikotaSyed Althaf
Jan 31, 2021·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Yudai TateishiTakeshi Kaneko
Jul 24, 2021·Indian Journal of Surgical Oncology·Arvind KumarSukhram Bishnoi
Jul 31, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Qing ZhouJunlin Zhou

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