PMID: 16527798Mar 11, 2006Paper

A meta-analysis of noninvasive weaning to facilitate liberation from mechanical ventilation

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
Karen E A BurnsMaureen O Meade

Abstract

To summarize the evidence comparing noninvasive positive pressure ventilation (NPPV) and invasive positive pressure ventilation (IPPV) weaning on mortality, ventilator associated pneumonia and the total duration of mechanical ventilation among invasively ventilated adults with respiratory failure. Meta-analysis of randomized and quasi-randomized studies comparing early extubation with immediate application of NPPV to IPPV weaning. We selected randomized studies that 1) included adults, with respiratory failure, invasively ventilated for at least 24 hr; 2) compared extubation with immediate application of NPPV to weaning using IPPV; and 3) reported at least one clinically important outcome. We searched MEDLINE (1966 to 2003), EMBASE (1980 to 2003) and the Cochrane Central Register of Controlled Trials (The Cochrane Library, Issue 2, 2003) for randomized controlled trials comparing NPPV and IPPV weaning. Additional data sources included personal files, conference proceedings and author contact. Two reviewers independently assessed trial quality and abstracted data. Five studies enrolling 171 patients demonstrated that compared to IPPV, noninvasive weaning decreased mortality (relative risk, 0.41 [95% confidence interval [CI] 0.22...Continue Reading

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Citations

Apr 29, 2008·Critical Care : the Official Journal of the Critical Care Forum·Massimo Antonelli, Giuseppe Bello
Apr 18, 2008·Critical Care : the Official Journal of the Critical Care Forum·Cristiane E TrevisanUNKNOWN Research Group in Mechanical Ventilation Weaning
Aug 20, 2008·Critical Care : the Official Journal of the Critical Care Forum·Mohamad F El-Khatib, Pierre Bou-Khalil
Jan 10, 2014·International Journal of Critical Illness and Injury Science·Anirban H Choudhuri
Mar 11, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Michael J Jacka
Aug 6, 2008·Der Anaesthesist·R Dembinski, R Rossaint
Nov 6, 2010·Chest·Salvador Díaz Lobato, Sagrario Mayoralas
Apr 2, 2013·Archivos de bronconeumología·Jorge ValenzuelaPablo Cruces
Oct 13, 2009·Archivos de bronconeumología·Luis Aurelio DíazMarcos I Restrepo
Apr 28, 2009·Infectious Disease Clinics of North America·Ilias I SiemposMatthew E Falagas
Sep 12, 2014·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Jul 8, 2011·Respiration; International Review of Thoracic Diseases·Yohei KidaMasakazu Ichinose
Apr 25, 2008·Critical Care Medicine·Nicholas S Ward, Kevin M Dushay
Sep 12, 2008·British Journal of Hospital Medicine·J J P Goldring, J A Wedzicha
Oct 9, 2018·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Vorawut ThanthitaweewatNaricha Chirakalwasan

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