A Meta-analysis of Studies Comparing Outcomes of Diverse Acellular Dermal Matrices for Implant-Based Breast Reconstruction

Annals of Plastic Surgery
Kyeong-Tae Lee, Goo-Hyun Mun

Abstract

The current diversity of the available acellular dermal matrix (ADM) materials for implant-based breast reconstruction raises the issue of whether there are any differences in postoperative outcomes according to the kind of ADM used. The present meta-analysis aimed to investigate whether choice of ADM products can affect outcomes. Studies that used multiple kinds of ADM products for implant-based breast reconstruction and compared outcomes between them were searched. Outcomes of interest were rates of postoperative complications: infection, seroma, mastectomy flap necrosis, reconstruction failure, and overall complications. A total of 17 studies met the selection criteria. There was only 1 randomized controlled trial, and the other 16 studies had retrospective designs. Comparison of FlexHD, DermaMatrix, and ready-to-use AlloDerm with freeze-dried AlloDerm was conducted in multiple studies and could be meta-analyzed, in which 12 studies participated. In the meta-analysis comparing FlexHD and freeze-dried AlloDerm, using the results of 6 studies, both products showed similar pooled risks for all kinds of complications. When comparing DermaMatrix and freeze-dried AlloDerm with the results from 4 studies, there were also no differe...Continue Reading

References

Mar 10, 2006·Plastic and Reconstructive Surgery·Neal HandelJ Arthur Jensen
Jul 3, 2008·Plastic and Reconstructive Surgery·Stephen R SullivanF Frank Isik
Feb 4, 2010·Plastic and Reconstructive Surgery·Yoon S ChunElof Eriksson
Jan 14, 2011·Plastic and Reconstructive Surgery·Allen S LiuLifei Guo
Aug 10, 2011·Annals of Plastic Surgery·George N CollisGalen Perdikis
Oct 28, 2011·Plastic and Reconstructive Surgery·Andrew J VardanianJaco H Festekjian
Feb 14, 2012·Plastic and Reconstructive Surgery·Scot B Glasberg, David Light
Apr 10, 2012·Clinics in Plastic Surgery·Angela Cheng, Michel Saint-Cyr
Sep 29, 2012·Plastic and Reconstructive Surgery·Akhil K SethJohn Y S Kim
Dec 29, 2012·Plastic and Reconstructive Surgery·Claudia R AlbornozEvan Matros
Feb 15, 2013·Annals of Plastic Surgery·Ahmed M S IbrahimSamuel J Lin
Apr 2, 2013·Annals of Plastic Surgery·Jason BusemanHenry C Vasconez
May 3, 2013·Annals of Plastic Surgery·Daniel Z LiuOtway Louie
Jun 22, 2013·Annals of Plastic Surgery·Brett F MichelottiJohn Potochny
Apr 16, 2014·Plastic and Reconstructive Surgery·Anne Warren PeledHani Sbitany
Sep 23, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M D BarberJ M Dixon
Oct 8, 2014·Plastic and Reconstructive Surgery. Global Open·James C YuenSuzanne Klimberg
Jul 17, 2015·Plastic and Reconstructive Surgery. Global Open·Christian EichlerMathias Warm
Sep 24, 2015·Plastic and Reconstructive Surgery·Kavitha RanganathanAdeyiza O Momoh
Oct 7, 2015·Annals of Surgical Oncology·Kyeong-Tae Lee, Goo-Hyun Mun
Feb 20, 2016·Plastic and Reconstructive Surgery. Global Open·David A PalaiaMichael H Rosenberg

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Citations

Dec 28, 2018·Plastic and Reconstructive Surgery·Andrew M SimpsonJayant P Agarwal
Feb 11, 2020·Annals of Plastic Surgery·Patrick S CottlerChris A Campbell
May 23, 2020·Plastic and Reconstructive Surgery. Global Open·Lindsey N UrquiaAlbert Losken
Apr 3, 2020·British Journal of Hospital Medicine·Victoria Teoh, Gerald Gui
Nov 18, 2020·Aesthetic Surgery Journal·Francis D GrazianoHani Sbitany
Nov 30, 2020·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Anna LuanRahim S Nazerali
Jun 22, 2021·Plastic and Reconstructive Surgery. Global Open·Brian P Tierney

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