A Metabolomic Overview of Follicular Fluid in Cows

Frontiers in Veterinary Science
Tatiane Melina GuerreiroRodrigo Ramos Catharino

Abstract

Follicular fluid (FF) protects the oocyte against proteolysis and extrusion during ovulation, providing an appropriate microenvironment that favors proper embryonic development; thereby, FF plays a key role in embryo quality. Being directly related to cattle breeding, studying FF is extremely important in livestock science to measure cattle fertility. This may eventually help to assess the quality of both meat and milk, products widely consumed worldwide. There is an important commercial interest in the evaluation and characterization of compounds present in the FF of livestock that present greater likelihood of pregnancy. Mass spectrometry is a great ally for this type of analysis and can provide quick and efficient screening for molecular markers in biological samples. The present study demonstrated the potential of high-resolution mass spectrometry in analyzing FF samples from two distinct groups of Nellore cows (Bos indicus): high and low fertility, as determined by the number of oocytes produced. We were able to delineate markers of interest for each group, which may ultimately be related to biochemical pathways that lead to higher or lower reproductive performance.

References

Nov 1, 1978·Clinics in Endocrinology and Metabolism·K P McNatty
Mar 1, 1988·Journal of Reproduction and Fertility·R G GosdenN Brown
Jan 28, 1999·Molecular and Cellular Endocrinology·J S RichardsT N Alliston
Mar 17, 1999·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·A Tsafriri, R Reich
Jun 14, 2000·Animal Reproduction Science·W R Butler
Sep 20, 2000·Journal of Agricultural and Food Chemistry·C L MirandaD R Buhler
Jul 27, 2002·Reproduction : the Official Journal of the Society for the Study of Fertility·N GérardF Seguin
Feb 20, 2003·Journal of Agricultural and Food Chemistry·Paola DugoGiovanni Dugo
Jul 3, 2004·Phytochemistry·Jan F Stevens, Jonathan E Page
Sep 21, 2004·Nature Medicine·Haibin WangSudhansu K Dey
Jan 19, 2005·British Journal of Pharmacology·Heather B Bradshaw, J Michael Walker
Feb 1, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Ian D WilsonEva M Lenz
Feb 8, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·Nicolas M OrsiSarah E Harris
Sep 27, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·J L M R LeroyA Van Soom
Nov 1, 2005·Theriogenology·Marc-André SirardClaude Robert
Feb 1, 1994·Theriogenology·A Romero-Arredondo, G E Seidel
Jan 18, 2007·Development, Growth & Differentiation·S NandiP S P Gupta
Oct 26, 2007·Theriogenology·J E P SantosR Sartori
Mar 13, 2008·JAMA : the Journal of the American Medical Association·Osama M H HabayebJustin C Konje
Dec 6, 2008·Reproduction in Domestic Animals = Zuchthygiene·B RenavilleA Prandi
May 6, 2009·Reproductive Biology and Endocrinology : RB&E·Alberto RevelliPaolo Rinaudo
Oct 2, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·Henry N JabbourJane E Norman
Apr 14, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·K BenderL Brennan
Oct 6, 2010·Plant Physiology·Richard A Dixon, Giulio M Pasinetti
Nov 3, 2010·Reproductive Biology and Endocrinology : RB&E·Diane M DuffyLane K Christenson
Jan 25, 2011·Animal Reproduction Science·S W WalshA C O Evans
May 26, 2011·Cold Spring Harbor Perspectives in Biology·Dominik SchwudkeAndrej Shevchenko
May 29, 2012·Experimental and Molecular Pathology·Christoph DornClaus Hellerbrand

❮ Previous
Next ❯

Citations

Oct 24, 2018·International Journal of Molecular Sciences·Priscila Silvana BertevelloSvetlana Uzbekova

❮ Previous
Next ❯

Software Mentioned

MetaboAnalyst
PLS
DA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.