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A metabolomics study: CdTe/ZnS quantum dots induce polarization in mice microglia

Chemosphere

Jan 14, 2020

Keyu HeMeng Tang

Abstract

In this study, a metabolomic analysis was used to reveal the neurotoxicity of the CdTe/ZnS QDs via microglia polarization. A gas chromatography-mass spectrometer (GC-MS) was applied to uncover the metabonomic changes in microglia (BV-2 cell line) after exposure to 1.25 μM CdTe/ZnS QDs. ...read more

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Study
Brain Tissue
Neurons
Microglia
Metabonomics
Laboratory mice
Extracellular
Cadmium telluride
Cell Respiration
Structure of Vein of Tail
Paper Details
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A metabolomics study: CdTe/ZnS quantum dots induce polarization in mice microglia

Chemosphere

Jan 14, 2020

Keyu HeMeng Tang

PMID: 31927360

DOI: 10.1016/j.chemosphere.2019.125629

Abstract

In this study, a metabolomic analysis was used to reveal the neurotoxicity of the CdTe/ZnS QDs via microglia polarization. A gas chromatography-mass spectrometer (GC-MS) was applied to uncover the metabonomic changes in microglia (BV-2 cell line) after exposure to 1.25 μM CdTe/ZnS QDs. ...read more

Mentioned in this Paper

Study
Brain Tissue
Neurons
Microglia
Metabonomics
Laboratory mice
Extracellular
Cadmium telluride
Cell Respiration
Structure of Vein of Tail

Similar Papers Found In These Feeds

Limbic System

The limbic system is comprised of several different parts of the brain involved in emotion, motivation, learning, and memory. Discover the latest research on the limbic system here.

Neurotoxicity, Inflammation & Neuroprotection

The end result of the inflammatory process, neurotoxicity and/or neuroprotection, is a function of the fine balance between the two cellular systems, i.e., of the complex signaling relationships between anti-inflammatory neuroprotective factors (neurotrophins and other chemical mediators) and proinflammatory neurotoxic factors (tnf, free radicals, certain cytokines, etc). Here are the latest discoveries pertaining to neurotoxicity, inflammation and neuroprotection.

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International Journal of Nanomedicine

Toxicity and serum metabolomics investigation of Mn-doped ZnS quantum dots in mice

International Journal of NanomedicineSeptember 10, 2019
Yanjie YangShaoping Ji
Paper Details
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