A method for modeling laterally asymmetric proton beamlets resulting from collimation

Medical Physics
Edgar GeloverDaniel E Hyer

Abstract

To introduce a method to model the 3D dose distribution of laterally asymmetric proton beamlets resulting from collimation. The model enables rapid beamlet calculation for spot scanning (SS) delivery using a novel penumbra-reducing dynamic collimation system (DCS) with two pairs of trimmers oriented perpendicular to each other. Trimmed beamlet dose distributions in water were simulated with MCNPX and the collimating effects noted in the simulations were validated by experimental measurement. The simulated beamlets were modeled analytically using integral depth dose curves along with an asymmetric Gaussian function to represent fluence in the beam's eye view (BEV). The BEV parameters consisted of Gaussian standard deviations (sigmas) along each primary axis (σ(x1),σ(x2),σ(y1),σ(y2)) together with the spatial location of the maximum dose (μ(x),μ(y)). Percent depth dose variation with trimmer position was accounted for with a depth-dependent correction function. Beamlet growth with depth was accounted for by combining the in-air divergence with Hong's fit of the Highland approximation along each axis in the BEV. The beamlet model showed excellent agreement with the Monte Carlo simulation data used as a benchmark. The overall passi...Continue Reading

References

Aug 1, 1996·Physics in Medicine and Biology·L HongM Urie
Oct 21, 2005·Physics in Medicine and Biology·Martin SoukupMarkus Alber
Feb 15, 2012·Physics in Medicine and Biology·Benjamin ClasieHanne M Kooy
Aug 21, 2013·Physics in Medicine and Biology·Liyong LinJames E McDonough

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Citations

Nov 29, 2015·International Journal of Radiation Oncology, Biology, Physics·Alexandra MoignierDaniel Hyer
Mar 5, 2016·Medical Physics·Frances C CharlwoodRanald I Mackay
Apr 28, 2020·Medical Physics·Blake R SmithWesley S Culberson
Mar 15, 2020·Medical Physics·Theodore J GeogheganDaniel E Hyer
Dec 14, 2018·Physics in Medicine and Biology·Carla WinterhalterSairos Safai
Mar 1, 2016·International Journal of Particle Therapy·Alexandra MoignierDaniel Hyer
Dec 20, 2017·Physics in Medicine and Biology·Carla WinterhalterSairos Safai
Jan 13, 2018·Physics in Medicine and Biology·C WinterhalterS Safai
Jun 5, 2021·Biomedical Physics & Engineering Express·T R WilloughbyP Kelly

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