PMID: 3747592Jul 1, 1986Paper

A method for repeated CSF sampling in the freely moving rat

Journal of Neuroscience Methods
M E KornhuberU Cimniak

Abstract

With the use of a holder mounted on the skull of rats, a cannula can be implanted so that one end rests on the atlanto-occipital membrane overlying the cisterna magna. Needles introduced through the cannula allow repeated access to the cisterna magna in the freely moving animal. This system is stable for periods of up to 4 weeks and is suited for repeated sampling of the cerebrospinal fluid.

References

Jul 1, 1979·Brain Research Bulletin·H J Bouman, T B Van Wimersma Greidanus
Aug 1, 1967·Comparative Biochemistry and Physiology·U S SealA W Erickson
Mar 14, 1983·Brain Research·W J SchwartzS M Reppert
Feb 1, 1981·Journal of Neuroscience Methods·P M Jones, I C Robinson

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Citations

May 15, 2002·Journal of Neuroscience Methods·Mascha P van den BergFrans W H M Merkus
Jan 1, 1996·Brain Research Bulletin·Y L HuangH A Hansson
May 10, 2013·PloS One·Christiane MühleJohannes Kornhuber
Aug 30, 2005·Journal of Pharmacological and Toxicological Methods·Mohammed El MoueddenMarc Mercken
Jul 30, 2014·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Graham K FarringtonDanica B Stanimirovic
Mar 15, 2006·BioTechniques·Pengfei SongCharles R Yates

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