A method for reproducing fatal idiopathic colitis (colitis X) in ponies and isolation of a clostridium as a possible agent

Equine Veterinary Journal
J F PrescottK Delaney

Abstract

Severe colitis was induced in two ponies after oral pretreatment with clindamycin and lincomycin, followed by intestinal content from two horses which had died from naturally-occurring idiopathic colitis. Two ponies treated with antibiotic alone, and two ponies treated with intestinal content alone, were unaffected. In a further study, three ponies treated on separate occasions with lincomycin, administered orally, died or were destroyed 67 to 72 h after initial treatment. No established salmonella, yersinia or campylobacter pathogens were isolated from these ponies, but a clostridium closely resembling Clostridium cadaveris was isolated as the predominant clostridium from them all and from the colonic content of one of six horses which died from naturally-occurring idiopathic colitis. It was not isolated from six horses with non-fatal diarrhoea. This clostridium is a candidate as an agent of some cases of fatal colitis in horses.

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Citations

Feb 1, 1995·Australian Veterinary Journal·M C StewartD R Hodgson
Jul 1, 1997·Equine Veterinary Journal·V BåverudA Gunnarsson
Jul 1, 1997·Equine Veterinary Journal·A GustafssonA Franklin
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May 1, 1993·Veterinary Pathology·C M JohnsonM C Roberts
Jan 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J PerrinJ Nicolet
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Apr 1, 1996·Clinical Microbiology Reviews·J G Songer
Jan 16, 1999·Journal of Clinical Microbiology·C HerholzR Straub

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