A methodological systematic review on surgical site infections following spinal surgery: part 1: risk factors

Spine
Albert F Pull ter GunneJoost J van Middendorp

Abstract

A methodological systematic review. To critically appraise the validity of risk factors for surgical site infection (SSI) after spinal surgery. SSIs lead to higher morbidity, mortality, and increased health care costs. Understanding which factors lead to an increased risk of SSI is important for the development of prophylactic protocols to counter this risk. To date, however, no review appraising the methodological quality of studies evaluating risk factors for spinal SSIs has been published. Contemporary studies identifying risk factors for SSI after spinal surgery were searched through the Medline and EMBASE databases (January 2001 to December 2010). References were retrieved and bias-prone study features were abstracted individually and independently by 2 authors. Twenty-four eligible studies were identified, including 9 (nested) case-control studies and 15 case series. Included studies covered wide variations of indications and surgical procedures. A total of 73 different types of factors were evaluated for the risk of an SSI of which 34 (47%) were reported to be significantly related to at least 1 study. Only the following risk factors-diabetes mellitus, obesity, and previous SSI-were confirmed more often (n = 11, 8, and 3...Continue Reading

References

Jun 1, 1973·Clinical Orthopaedics and Related Research·J P KostuikJ E Hall
Aug 1, 1995·Journal of Spinal Disorders·D M AbbeyR D Scalley
Dec 26, 2001·Journal of Orthopaedic Trauma·G R RechtineA M Chrin
Apr 30, 2002·Spine·Stephen P BancoSheila Murphey
May 30, 2002·Annals of Surgery·Robert C G MartinDavid P Jaques
Feb 1, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anucha ApisarnthanarakVictoria J Fraser
Mar 26, 2003·Journal of Neurosurgery·Margaret A OlsenVictoria J Fraser
Jan 26, 2005·Archives of Internal Medicine·Daniel J BrotmanRalph G O'Brien
Jun 17, 2005·Spine·Andrew FangDavid S Bradford
Jul 22, 2006·Scandinavian Journal of Infectious Diseases·Zeina A KanafaniSouha S Kanj
Mar 22, 2007·JAMA : the Journal of the American Medical Association·Harriette G C Van SpallRobert A Fowler
Oct 13, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·N Deborah FriedmanKeith S Kaye
Dec 21, 2007·The Journal of Spinal Cord Medicine·Saad B ChaudharyMitchell F Reiter
Feb 19, 2008·Cadernos de saúde pública·Maria de Jesus Mendes da FonsecaMarília Sá Carvalho
May 2, 2008·Drugs & Aging·Michael H YoungPreeti N Malani
Jun 6, 2008·The Journal of the American Academy of Orthopaedic Surgeons·Rick C Sasso, Ben J Garrido
Jul 16, 2008·Journal of Clinical Epidemiology·R H H GroenwoldA W Hoes
Sep 11, 2008·Journal of Studies on Alcohol and Drugs·Keith HumphreysKenneth R Weingardt
Oct 4, 2008·Best Practice & Research. Clinical Anaesthesiology·Ashley M Shilling, Jacob Raphael
Feb 20, 2009·Clinical Orthopaedics and Related Research·Sam ChenMontri D Wongworawat
Aug 1, 2009·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Kelley M BostonKristy O Murray
Jan 13, 2010·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Albert F Pull ter GunneDavid B Cohen
Jan 19, 2010·The Spine Journal : Official Journal of the North American Spine Society·Albert F Pull ter GunneDavid B Cohen
May 7, 2010·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·J J P SchimmelJ van Limbeek
Jul 17, 2010·Journal of Spinal Disorders & Techniques·Kang-Wu ChenRuo-Fu Zhu

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Citations

Sep 25, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Dan XingRui Feng
Jul 6, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Dima Y AbdallahJohn P McCabe
Apr 24, 1999·Trends in Neurosciences·D H EdwardsF B Krasne
Apr 23, 2013·Journal of Neurosurgery. Spine·Albert F Pull Ter GunneJoost J van Middendorp
Jan 19, 2013·World Journal of Orthopedics·Vishal HegdeRussel C Huang
Sep 17, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Dima Y AbdallahJohn P McCabe
Jan 25, 2014·The Spine Journal : Official Journal of the North American Spine Society·Michael J LeeJens R Chapman
Sep 27, 2014·Journal of Neurosurgery. Spine·Nickalus R KhanPaul Klimo
Jan 31, 2016·The Spine Journal : Official Journal of the North American Spine Society·Delio Eulalio MartinsMarcelo Wajchenberg
Apr 8, 2014·Neurosurgery Clinics of North America·James A StadlerJohn C Liu
May 6, 2014·Neuroimaging Clinics of North America·Morgan C Willson, Jeffrey S Ross
Jan 26, 2016·The Spine Journal : Official Journal of the North American Spine Society·Sleiman HaddadAlexander R Vaccaro
Aug 8, 2013·The Journal of Hospital Infection·R HuttunenJ Syrjänen
Aug 19, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Fei MengXianzhong Meng
Oct 4, 2015·Insights Into Imaging·Ajay MalhotraKhalid M Abbed
Apr 11, 2015·Journal of Neurosurgery. Spine·Michael J DurkinDeverick J Anderson
Apr 9, 2013·Journal of Spinal Disorders & Techniques·Amina RehmanCasey Freeman
Mar 23, 2015·The Spine Journal : Official Journal of the North American Spine Society·Rajeev SubramanyamAnna M Varughese
Mar 22, 2014·The Spine Journal : Official Journal of the North American Spine Society·Osa EmohareMatthew M Kang
Sep 30, 2014·The Spine Journal : Official Journal of the North American Spine Society·Kris E RadcliffAlexander R Vaccaro
Sep 10, 2014·Clinical Orthopaedics and Related Research·Bryce A BasquesJonathan N Grauer
May 14, 2016·International Wound Journal·Christian WillyV Sreenath Reddy
Nov 11, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Daisuke KudoYoichi Shimada
Feb 7, 2014·The Journal of Bone and Joint Surgery. American Volume·Gertraud GradlDavid Ring
Mar 21, 2018·Der Orthopäde·Burkhard LehnerNicholas A Beckmann
Mar 27, 2018·Clinical Spine Surgery : a Spine Publication·Joseph S ButlerAlexander R Vaccaro
Oct 8, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Nevil GhodasaraJan Fritz
Jun 13, 2017·Spine·David S CasperChristopher K Kepler
Apr 10, 2020·The Cochrane Database of Systematic Reviews·Saori GotoYoshiharu Sakai
Jun 18, 2016·Experimental and Therapeutic Medicine·Chenliang ZhouJing Qu
May 8, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Sleiman HaddadUNKNOWN European Spine Study Group

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