A methodology for in silico endovascular repair of abdominal aortic aneurysms

Biomechanics and Modeling in Mechanobiology
André HemmlerMichael W Gee

Abstract

Endovascular aneurysm repair (EVAR) can involve some unfavorable complications such as endoleaks or stent-graft (SG) migration. Such complications, resulting from the complex mechanical interaction of vascular tissue, SG and blood flow or incompatibility of SG design and vessel geometry, are difficult to predict. Computational vascular mechanics models can be a predictive tool for the selection, sizing and placement process of SGs depending on the patient-specific vessel geometry and hence reduce the risk of potential complications after EVAR. In this contribution, we present a new in silico EVAR methodology to predict the final state of the deployed SG after intervention and evaluate the mechanical state of vessel and SG, such as contact forces and wall stresses. A novel method to account for residual strains and stresses in SGs, resulting from the precompression of stents during the assembly process of SGs, is presented. We suggest a parameter continuation approach to model various different sizes of SGs within one in silico EVAR simulation which can be a valuable tool when investigating the issue of SG oversizing. The applicability and robustness of the proposed methods are demonstrated on the example of a synthetic abdomina...Continue Reading

References

Jul 1, 1968·Circulation Research·T E CarewD J Patel
Jan 1, 1997·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T ChuterB Risberg
Feb 15, 2001·Journal of Vascular Surgery·H G BeebeUNKNOWN Vanguard Endograft Trial Investigators
May 22, 2001·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·I V MohanUNKNOWN EUROSTAR COLLABORATORS
Jan 11, 2002·Journal of Biomechanical Engineering·D H WangD A Vorp
Mar 29, 2003·Journal of Vascular Surgery·Mark F FillingerFrancis E Kennedy
Jan 14, 2004·Journal of Vascular Surgery·Thomas L ForbesKenneth A Harris
Dec 16, 2004·Annals of Vascular Surgery·Sergio M SampaioPeter Gloviczki
May 12, 2005·Journal of Biomechanics·Jonathan P Vande GeestDavid A Vorp
Jul 20, 2006·Journal of the Royal Society, Interface·T Christian GasserGerhard A Holzapfel
Sep 26, 2006·Journal of Biomechanical Engineering·Garrett J Hall, Eric P Kasper
Dec 22, 2006·Annals of the New York Academy of Sciences·Jonathan P Vande GeestDavid A Vorp
Apr 3, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·F CochennecF Roudot-Thoraval
Feb 1, 2008·The New England Journal of Medicine·Roger M Greenhalgh, Janet T Powell
May 20, 2008·Journal of Vascular Surgery·T Christian GasserJesper Swedenborg
Jun 11, 2008·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Ludovic CanaudJean-Phillipe Berthet
Jul 23, 2008·Journal of Biomechanics·C KleinstreuerM A Farber
May 12, 2009·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·J van PrehnJ A van Herwaarden
Feb 10, 2010·Biomechanics and Modeling in Mechanobiology·A MaierW A Wall
Apr 1, 2010·Biomechanics and Modeling in Mechanobiology·Darren HaskettJonathan Vande Geest
Apr 13, 2010·The New England Journal of Medicine·UNKNOWN United Kingdom EVAR Trial InvestigatorsMark J Sculpher
May 8, 2010·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T C GasserJ Roy
Nov 12, 2010·Medical Engineering & Physics·F AuricchioB Verhegghe
Jan 11, 2011·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·F L MollUNKNOWN European Society for Vascular Surgery
Feb 11, 2011·Biomechanics and Modeling in Mechanobiology·P MoireauJ-F Gerbeau
Mar 1, 2009·Seminars in Interventional Radiology·Geert MaleuxSam Heye
Jul 19, 2011·Journal of Biomechanics·Madhavan L RaghavanErasmo Simao da Silva
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Nicolas DemangetJean-Pierre Favre
Dec 23, 2011·Journal of Biomechanics·J D Humphrey, G A Holzapfel
Feb 7, 2012·Journal of Vascular Surgery·Kathleen K LinMadhavan L Raghavan
Jul 31, 2012·Journal of the Mechanical Behavior of Biomedical Materials·S De BockB Verhegghe
Feb 12, 2013·Computers in Biology and Medicine·F AuricchioS Trimarchi
Feb 23, 2013·Medical Engineering & Physics·Stefano MorlacchiFrancesco Migliavacca
May 21, 2013·Journal of Vascular Surgery·Robert W ChangBradley Hill
Aug 7, 2013·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Nicolas DemangetJean-Pierre Favre
Dec 3, 2013·The International Journal of Angiology : Official Publication of the International College of Angiology, Inc·Manfred KalteisHerbert Lugmayr

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Citations

Feb 6, 2020·International Journal for Numerical Methods in Biomedical Engineering·André HemmlerDeon Bezuidenhout
Jul 18, 2019·International Journal for Numerical Methods in Biomedical Engineering·André HemmlerMichael W Gee
Mar 6, 2019·Biomechanics and Modeling in Mechanobiology·André HemmlerMichael W Gee
Feb 16, 2020·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·S WolkC Reeps
Oct 25, 2020·International Journal for Numerical Methods in Biomedical Engineering·Claire DupontPascal Haigron
Mar 9, 2021·Biomechanics and Modeling in Mechanobiology·Alberto CoccarelliSanjay Pant
Aug 26, 2021·Biomechanics and Modeling in Mechanobiology·Xiaoxin KanXiao Yun Xu
Sep 8, 2021·International Journal for Numerical Methods in Biomedical Engineering·Stéphane AvrilSandra Rugonyi

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