A microbiological and immunological study of endodontic-periodontic lesions

Journal of Endodontics
H KuriharaY Murayama

Abstract

The microflora and humoral immune response in tissue from the periodontal pockets and root canals of five teeth with endodontic-periodontic lesions were examined. We found more microbes in the periodontal pockets than in the root canals. The flora in the periodontal pockets was dominated by rods and motile organisms, whereas that in the root canals was largely rods and cocci. We detected no spirochetes in the root canals. The cultivable microflora in the periodontal pockets comprised a high number of different species of bacteria, whereas those in the root canals included only a small number of species. There was no correlation between microbial isolates and antibody titer in the apical tissues or periodontal pockets. We conclude from these studies that the microflora of infected root canals is simple and limited, and that the local humoral immune response does not seem to affect the pathogenesis of disease directly.

Citations

Sep 10, 2009·Australian Dental Journal·P V Abbott, J Castro Salgado
Apr 6, 2006·International Endodontic Journal·I G K StassenR J G De Moor
Sep 2, 2015·Clinical Oral Investigations·Markus ZarubaPatrick R Schmidlin
May 12, 2012·ISRN Dentistry·Elizangela Partata ZuzaBenedicto Egbert Corrêa de Toledo
Nov 15, 2011·International Endodontic Journal·A C DidilescuS I Stratul
Oct 23, 2002·Journal of Clinical Periodontology·M ZehnderG Hasselgren
Feb 19, 1998·Oral Microbiology and Immunology·A Le GoffM Bonnaure-Mallet
Apr 11, 2014·The Bulletin of Tokyo Dental College·Rie FujiiMasahiro Furusawa
Oct 13, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·M Zehnder
Sep 9, 2021·Clinical Oral Investigations·Diego José GambinMicheline Sandini Trentin

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