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A microRNA profile in Fmr1 knockout mice reveals microRNA expression alterations with possible roles in fragile X syndrome

bioRxiv

Jan 26, 2014

Ting Ting LiuYue-Sheng Long

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Abstract

Fragile X syndrome (FXS), a common form of inherited mental retardation, is caused by a loss of expression of the fragile X mental retardation protein (FMRP). FMRP is involved in brain functions by interacting with mRNAs and microRNAs (miRNAs) that selectively control gene expression at...read more

Mentioned in this Paper

Down-Regulation
Fragile X Syndrome
Gene Expression
Hippocampus (Brain)
Luciferases
Mental Retardation
Laboratory mice
Pathology
RNA, Messenger
Fragile X Mental Retardation Protein
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  • A microRNA profile in Fmr1 knockout mice reveals microRNA expression alterations with possible roles in fragile X syndrome

    bioRxiv

    Jan 26, 2014

    Ting Ting LiuYue-Sheng Long

    PMID: 990002071

    DOI: 10.1101/002071

    Abstract

    Fragile X syndrome (FXS), a common form of inherited mental retardation, is caused by a loss of expression of the fragile X mental retardation protein (FMRP). FMRP is involved in brain functions by interacting with mRNAs and microRNAs (miRNAs) that selectively control gene expression at...read more

    Mentioned in this Paper

    Down-Regulation
    Fragile X Syndrome
    Gene Expression
    Hippocampus (Brain)
    Luciferases

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