A mini pig model for visualization of perforator flap by using angiography and MIMICS.

Surgical and Radiologic Anatomy : SRA
Jin MeiMaolin Tang

Abstract

Research performed using animal models has assisted in the understanding of flap anatomy and physiology. Pigs' vasculature in the skin is anatomically and physiologically similar to human, making it an ideal model for research. Until now, most vascular imaging studies are of two-dimensions. The aim of this study is to provide a three-dimensional (3D) model that reveals detailed architecture of the vascular network of the porcine, for accurate quantitative assessment. Five Guangxi Bama minipigs were anaesthetized intramuscularly and underwent whole body lead oxide-gelatin injection. Spiral computed tomography scanning was performed on the subjects and three-dimensional reconstructions were made. Another minipig was used, and underwent Cardiografin injection. 3D-reconstruction was executed in vivo. All subjects were then dissected by layers to document the individual perforators. Angiography using perfusion with lead oxide-gelatine mixture has the advantage of illustrating distinctively the vessels and their perforating branches. However, it is incapable of displaying other tissues structures. Angiography through perfusion with Cardiografin in vivo has the advantage of demonstrating the relationship between arteries and bones. Ye...Continue Reading

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Citations

Jun 2, 2012·The Journal of Surgical Research·Carole Y VillamariaMichael R Davis
Aug 29, 2019·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Yi ZhanJian Qi

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