A mixed odontogenic sarcoma: A challenging histopathologic case and brief review of the literature

Journal of Oral and Maxillofacial Pathology : JOMFP
Saede Atarbashi-MoghadamSepideh Mokhtari

Abstract

Ameloblastic fibro-odontosarcoma (AFOS) is an extremely rare malignant mixed odontogenic tumor. The ectomesenchymal part of the neoplasm shows malignancy, whereas the epithelial component is rather benign. In addition, small areas with deposition of enamel matrix and dentine material are seen. The rarity of this neoplasm and microscopic similarities with other malignant and benign tumors can lead to diagnostic problems. Here, we describe the histopathologic features of a new case of AFOS of the mandible in a 34-year-old female patient. It is essential for oral pathologists to be familiar with the microscopic features of this rare neoplasm to have a proper diagnosis. This is also the first reported case of AFOS that closely resembles osteosarcoma in some areas.

References

Apr 30, 2015·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Al Haitham Al ShetawiMark L Urken
Jul 25, 2015·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Fereydoun PourdaneshOmid Soltaninia

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Methods Mentioned

BETA
biopsy
X-ray
dissection

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