A mixture of pesticides at environmental concentrations induces oxidative stress and cholinergic effects in the neotropical fish Rhamdia quelen.

Ecotoxicology
Aline Teixeira MarinsVania Lucia Loro

Abstract

The insecticides imidacloprid (IMI), a neonicotinoid, and propoxur (PRO), an N-methylcarbamate compound, are pesticides widely used throughout the world. Although they are not used together to combat pests, both are often found in freshwater near agricultural areas. Thereby, the goal of this study was to evaluate the additive effects of IMI and PRO mixtures at environmental concentrations in relation to isolated compounds on Rhamdia quelen, a neotropical fish. The fish was exposed to IMI (0.11 µg/L), PRO (0.039 µg/L), or Mix (0.11 µg/L IMI plus 0.039 µg/L PRO) during 96 h. Glutathione S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), acetylcholinesterase (AChE) activities were determined. To verify oxidative damage thiobarbituric acid reactive substances (TBARS), protein carbonyl (PC), reactive oxygen species contents (ROS), antioxidant capacity against peroxides (ACAP) were determined in gills, liver, brain and muscle. The results shows that a mixture of these pesticides at environmental concentrations inhibited acetylcholinesterase activity in the brain and induced oxidative damage in all analyzed tissues. These results reinforce the hypothesis that mixture of contaminants present in environment could induce ad...Continue Reading

References

Jan 1, 1990·Methods in Enzymology·H H Draper, M Hadley
Jul 1, 1961·Biochemical Pharmacology·G L ELLMANR M FEATHER-STONE
Mar 17, 2010·The Science of the Total Environment·David J SpurgeonStephen R Stürzenbaum
Nov 16, 2010·Aquatic Toxicology·Volodymyr I Lushchak
Nov 3, 2011·Journal of Exposure Science & Environmental Epidemiology·Elvira V BräunerMette Sørensen
Dec 3, 2013·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Manish Raj Pandey, Huarong Guo
Jun 19, 2014·Environmental Science and Pollution Research International·David GibbonsPierre Mineau
Jan 22, 2015·Journal of Agricultural and Food Chemistry·Weili GeJun Wang
Apr 7, 2015·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Fabiano A OliveiraMarília M Melo
May 7, 2015·Neurotoxicology and Teratology·Emily B CrosbyEdward D Levin
Aug 5, 2016·Environmental Toxicology and Chemistry·Fernando G IturburuMirta L Menone
Dec 22, 2017·Chemosphere·Carlos Eduardo Delfino VieiraCláudia Bueno Dos Reis Martinez
Jan 30, 2018·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·John A FrewJohn W Nichols
Feb 22, 2018·Bulletin of Environmental Contamination and Toxicology·Carjone Rosa GonçalvesVania Lucia Loro
Feb 23, 2018·Integrated Environmental Assessment and Management·Tatiana Heid FurleyBryan W Brooks
Feb 27, 2018·Molecular and Cellular Biochemistry·Matheus D BaldisseraBernardo Baldisserotto
Apr 18, 2018·Bulletin of Environmental Contamination and Toxicology·Fernando G IturburuMirta L Menone
Dec 17, 2019·Ecotoxicology and Environmental Safety·Eduardo Stringini SeveroVania Lucia Loro
Mar 14, 2020·Bulletin of Environmental Contamination and Toxicology·Aline Teixeira MarinsVania Lucia Loro
Sep 22, 2020·Ecotoxicology and Environmental Safety·Carjone GonçalvesVania Lucia Loro

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Citations

Aug 17, 2021·Environmental Science & Technology·Sarah KönemannColette Vom Berg

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