A mobile device application to reduce medication errors and time to drug delivery during simulated paediatric cardiopulmonary resuscitation: a multicentre, randomised, controlled, crossover trial

The Lancet Child & Adolescent Health
Johan N SiebertPedAMINES Trial Group

Abstract

Vasoactive drug preparation for continuous infusion in children is both complex and time consuming and places the paediatric population at higher risk than adults for medication errors. We developed a mobile device application (app) as a step-by-step guide for the preparation to delivery of drugs requiring continuous infusion. The app has been previously tested during simulation-based resuscitations in a previous single-centre trial. In this trial, our aim was to assess this app in various hospital settings. We did a prospective, multicentre, randomised, controlled, crossover trial to compare this app with an internationally used drug-infusion-rates table for the preparation of continuous drug infusion during standardised, simulation-based, paediatric post-cardiac arrest scenarios using a high-fidelity manikin. The scenarios were split into two study periods to assess the two preparation methods consecutively, separated by a washout distraction manoeuvre. Nurses in six paediatric emergency centres in Switzerland were randomly assigned (1:1) to start the scenario with either the app or the infusion-rates table and then complete the scenario using the other preparation method. The primary endpoint was the proportion of participan...Continue Reading

Citations

Sep 2, 2020·Acta Paediatrica·Haiko Kurt JahnUNKNOWN Paediatric Emergency Research in the United Kingdom, Ireland (PERUKI)
Nov 17, 2020·British Journal of Clinical Pharmacology·Rachel BryanSue Jordan
Mar 26, 2021·European Journal of Pediatrics·Haiko Kurt JahnUNKNOWN Paediatric Emergency Research United Kingdom and Ireland (PERUKI)
Aug 31, 2021·JAMA Network Open·Johan N SiebertUNKNOWN Pediatric Accurate Medication in Emergency Situations (PedAMINES) Prehospital Group

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