A Model for Prediction of In-Hospital Mortality in Patients with Subarachnoid Hemorrhage.

Neurocritical Care
Mónica Mourelo-FariñaRita Galeiras

Abstract

Despite being a rare cause of stroke, spontaneous subarachnoid hemorrhage (SAH) is associated with high mortality rates. The prediction models that are currently being used on SAH patients are heterogeneous, and few address premature mortality. The aim of this study was to develop a mortality risk stratification score for SAH. A retrospective study was carried out with 536 patients diagnosed with SAH who had been admitted to the intensive care unit (ICU) at the University Hospital Complex of A Coruña (Spain) between 2003 and 2013. A multivariate logistic regression model was developed to predict the likelihood of in-hospital mortality, adjusting it exclusively for variables present on admission. A predictive equation of in-hospital mortality was then computed based on the model's coefficients, along with a points-based risk-scoring system. Its discrimination ability was also tested based on the area under the receiver operating characteristics curve and compared with previously developed scores. The mean age of the patients included in this study was 56.9 ± 14.1 years. Most of these patients (73.9%) had been diagnosed with aneurysmal SAH. Their median length of stay was 7 days in the ICU and 20 days in the general hospital ward...Continue Reading

References

Jul 13, 1974·Lancet·G Teasdale, B Jennett
May 8, 2000·Stroke; a Journal of Cerebral Circulation·T IngallR Bonita
Feb 7, 2001·Brain : a Journal of Neurology·J van Gijn, G J Rinkel
Apr 20, 2004·Critical Care Medicine·Jan ClaassenStephan A Mayer
May 4, 2004·Statistics in Medicine·Lisa M SullivanRalph B D'Agostino
Aug 12, 2005·Neurosurgery·Wouter Jan SchuilingGabriël J E Rinkel
Sep 15, 2005·Neurocritical Care·David S Rosen, R Loch Macdonald
Jun 16, 2007·Stroke; a Journal of Cerebral Circulation·Axel J RosengartR Loch Macdonald
Dec 18, 2010·Neurocirugía·R SarabiaM F Muñoz
Nov 10, 2012·Neurocritical Care·Blessing N R JajaR Loch Macdonald
Jan 15, 2014·Neurocritical Care·Vivien H LeeShyam Prabhakaran
Dec 24, 2014·World Neurosurgery·Ann-Christin von VogelsangYvonne Wengström
Sep 1, 2015·Surgical Neurology International·Benjamin W Y LoMitchell A H Levine
Sep 4, 2015·Critical Care : the Official Journal of the Critical Care Forum·Hector LantiguaStephan A Mayer
Nov 10, 2015·JAMA Neurology·Sureerat SuwatcharangkoonStephan A Mayer
Mar 16, 2016·Neurocirugía·Pedro David Delgado-LópezJosé Manuel Castilla-Díez
May 1, 2016·Annals of Neurology·Jens WitschJan Claassen
Jan 20, 2018·BMJ : British Medical Journal·Blessing N R JajaUNKNOWN SAHIT collaboration
Feb 8, 2018·World Neurosurgery·Yasser B AbulhasanJeanne Teitelbaum
Jun 8, 2019·Acta Anaesthesiologica Scandinavica·Markus Harboe OlsenKirsten Møller
Jul 25, 2019·Neurosurgical Review·Philipp HendrixChristoph J Griessenauer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.