A model for the roll-out of comprehensive adult male circumcision services in African low-income settings of high HIV incidence: the ANRS 12126 Bophelo Pele Project.

PLoS Medicine
Pascale LissoubaBertran Auvert

Abstract

World Health Organization (WHO)/Joint United Nations Programme on AIDS (UNAIDS) has recommended adult male circumcision (AMC) for the prevention of heterosexually acquired HIV infection in men from communities where HIV is hyperendemic and AMC prevalence is low. The objective of this study was to investigate the feasibility of the roll-out of medicalized AMC according to UNAIDS/WHO operational guidelines in a targeted African setting. The ANRS 12126 "Bophelo Pele" project was implemented in 2008 in the township of Orange Farm (South Africa). It became functional in 5 mo once local and ethical authorizations were obtained. Project activities involved community mobilization and outreach, as well as communication approaches aimed at both men and women incorporating broader HIV prevention strategies and promoting sexual health. Free medicalized AMC was offered to male residents aged 15 y and over at the project's main center, which had been designed for low-income settings. Through the establishment of an innovative surgical organization, up to 150 AMCs under local anesthesia, with sterilized circumcision disposable kits and electrocautery, could be performed per day by three task-sharing teams of one medical circumciser and five n...Continue Reading

References

Apr 12, 2002·The New England Journal of Medicine·Xavier CastellsaguéUNKNOWN International Agency for Research on Cancer Multicenter Cervical Cancer Study Group
Apr 21, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Bertran AuvertBrian Williams
Jan 22, 2005·Critical Reviews in Oncology/hematology·Anna Maria MosconiChristine Theodore
Jul 11, 2006·PLoS Medicine·Brian G WilliamsBertran Auvert
Mar 16, 2007·BMC Infectious Diseases·Nico J D NagelkerkeRobert C Bailey
Aug 2, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Ingrid V BassettRochelle P Walensky
Jan 30, 2008·AIDS and Behavior·Witness MoyoAudrey Pettifor
Mar 5, 2008·AIDS·Helen A WeissCatherine A Hankins
Oct 11, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Becky L GenbergUNKNOWN NIMH Project Accept Study Team (HPTN 043)
Oct 22, 2008·AIDS and Behavior·Audrey PettiforSinead Delany-Moretlwe
Feb 18, 2009·The Journal of Infectious Diseases·Joelle Sobngwi-TambekouBertram Auvert
Mar 27, 2009·The New England Journal of Medicine·Aaron A R TobianRonald H Gray
Apr 17, 2009·The Cochrane Database of Systematic Reviews·Nandi SiegfriedJimmy Volmink
Nov 11, 2009·PLoS Medicine·UNKNOWN UNAIDS/WHO/SACEMA Expert Group on Modelling the Impact and Cost of Male Circumcision for HIV Prevention
Jan 26, 2010·PLoS Medicine·Agnes BinagwahoStefano Bertozzi

❮ Previous
Next ❯

Citations

Aug 28, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·David C SokalMark A Barone
Jun 10, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Brian G WilliamsEleanor Gouws
Oct 31, 2012·Bulletin of the World Health Organization·Amy Herman-RoloffKawango Agot
Feb 25, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Mark A BaroneMarc Goldstein
Apr 20, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Samuel KanyagoMark J Siedner
Mar 12, 2013·The Journal of Urology·Kristin ChrouserSifuni Koshuma
Dec 22, 2012·The Lancet Infectious Diseases·Larry W ChangSteven J Reynolds
Jul 19, 2011·The Journal of the Association of Nurses in AIDS Care : JANAC·Jennifer FurinJonas Rigodon
May 6, 2015·Social Science & Medicine·Justin O ParkhurstEleanor Hutchinson
Jul 22, 2015·Developing World Bioethics·Bridget Haire, Christopher Jordens
Oct 5, 2011·Journal of the International AIDS Society·Brian WilliamsAlex Welte
Mar 1, 2012·BMC Pediatrics·Brian J MorrisAdrian Mindel
Jun 23, 2012·Journal of Sex Research·Alain Giami, Christophe Perrey
Mar 2, 2016·Journal of the International AIDS Society·Andrew J ShattockRichard T Gray
Apr 4, 2017·African Journal of AIDS Research : AJAR·Sarah Smith LunsfordEsther Karamagi

❮ Previous
Next ❯

Methods Mentioned

BETA
circumcision

Software Mentioned

MC MOVE

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.