A modified and cost-effective method for hair cortisol analysis

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
Lianbin XiangGailen D Marshall

Abstract

Hair cortisol may hold potential as a biomarker for assessment of chronic psychological stress. We report a modified and cost-effective method to prepare hair samples for cortisol assay. Hair samples were ground using an inexpensive ball grinder - ULTRA-TURRAX tube drive. Cortisol was extracted from the powder under various defined conditions. The data showed that the optimal conditions for this method include cortisol extraction at room temperature and evaporation using a stream of room air. These findings should allow more widespread research using economical technology to validate the utility of hair cortisol as a biomarker for assessing chronic stress status.

References

Feb 26, 2000·Forensic Science International : Synergy·R Wennig
Feb 26, 2000·Forensic Science International : Synergy·V CirimeleB Ludes
Jun 3, 2000·Annual Review of Immunology·J D AshwellM S Vacchio
May 26, 2001·The Journal of Endocrinology·E M Sternberg
Dec 14, 2004·Clinical Biochemistry·Jean-Sébastien RaulPascal Kintz
Feb 18, 2006·General and Comparative Endocrinology·Matthew D DavenportJerrold S Meyer
Apr 21, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Fritz Pragst, Marie A Balikova
Jun 3, 2009·Nature Reviews. Endocrinology·George P Chrousos
Jul 18, 2009·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·S ThomsonS H M Van Uum
Jan 26, 2010·Forensic Science International : Synergy·R GowG Koren
May 18, 2010·Psychoneuroendocrinology·L DettenbornC Kirschbaum
Jun 15, 2010·Progress in Brain Research·Lindsay K Smith, John A Cidlowski
Mar 18, 2011·Psychoneuroendocrinology·Susann SteudteThomas Elbert
Apr 26, 2011·Steroids·Laura ManenschijnElisabeth F C van Rossum
Jul 31, 2012·The Journal of Clinical Endocrinology and Metabolism·L ManenschijnE F C van Rossum

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved