A modified inactivation-inhibition method for determining the serum activity of alkaline phosphatase isoenzymes

Clinica Chimica Acta; International Journal of Clinical Chemistry
J StĕpánJ Kolár

Abstract

A procedure using heat inactivation and L-phenylalanine inhibition to quantitate the activities of bone, liver and intestinal alkaline phosphatase isoenzymes in human serum was confirmed by alkaline phosphatase isoenzyme analysis using an electrophoretic procedure. The results of this assay were compared with the radionuclear 85Sr test, and gamma-glutamyl transpeptidase activity in a group of patients with hepatobiliary and bone diseases.

Citations

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Related Concepts

Alkaline Phosphatase
Skeletal Bone
Malignant Bone Neoplasm
Use-Effectiveness
Gamma-glutamyl transferase
Intestines
Alloenzymes
Liver
Liver Dysfunction
Study, Methodological

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