A molecular light switch Ru complex and quantum dots for the label-free, aptamer-based detection of thrombin

The Analyst
Wenliang SunShuo Shi

Abstract

A simple, label-free method for the detection of thrombin has been developed based on the conformational transition of aptamer in the presence of the target by using a molecular light switch, Ru polypyridine complex, and quantum dots as novel fluorescence probes in aqueous solution.

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Dec 13, 2012·Chemical Reviews·Hongquan ZhangX Chris Le
Aug 15, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Shuyu ZhangHui Wei
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