A molecular take on Aesop's The oak and the reeds

Cell
Corentin J Moevus, Eric C Greene

Abstract

Ngo et al. use single-molecule methods to show that DNA can be more readily displaced from one side of a nucleosome relative to the other side. This unexpected mechanical asymmetry may offer a path of least resistance, allowing RNA polymerases to traverse nucleosomes if they approach from the correct direction.

References

Aug 1, 2009·Science·Courtney HodgesCarlos Bustamante

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Citations

Mar 19, 2016·The Journal of Physical Chemistry. B·Lennart de BruinHelmut Schiessel

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