A morphological study of the foveal avascular zone in patients with diabetes mellitus using optical coherence tomography angiography

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Gong DiDong Fangtian

Abstract

To investigate the area and radius of the foveal avascular zone (FAZ) in patients with diabetes mellitus (DM) using optical coherence tomography (OCT) angiography. Sixty-five patients with DM (113 eyes) and 62 healthy controls (85 eyes) were included in the study. All of the participants underwent examination with OCT angiography. The vertical radius (VR), horizontal radius (HR) and area of the FAZ were measured. The differences in HR, VR and area between the control and DM groups were statistically significant (p = 0.01, 0.00 and 0.00, respectively). There were no statistically significant differences between the control group and the no-diabetic retinopathy (DR) group in HR or VR (p = 0.07 and 0.08, respectively), but there was a statistically significant difference in area (p = 0.04). The size of the FAZ was greater in patients with DR compared to the control group. The differences in HR, VR and area were statistically significant (p = 0.01, 0.00 and 0.00, respectively). In addition, the clinically significant macular oedema (CSME) group also had a larger FAZ area than the non-CSME group (p = 0.02). Patients with DM had a larger FAZ, and patients with more severely damaged retinas had a much larger FAZ. OCT angiography is a ...Continue Reading

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Citations

May 14, 2016·Expert Review of Medical Devices·Rupesh AgrawalAniruddha Agarwal
May 14, 2016·American Journal of Ophthalmology·Fabio ScarinciAmani A Fawzi
Sep 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Eduardo A NovaisJay S Duker
Jul 2, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Joel HanhartYaakov Rozenman
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