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A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

The Journal of Antimicrobial Chemotherapy

Dec 4, 2019

Stephanie W LoGlobal Pneumococcal Sequencing Consortium

Abstract

We reported tet(S/M) in Streptococcus pneumoniae and investigated its temporal spread in relation to nationwide clinical interventions. We whole-genome sequenced 12 254 pneumococcal isolates from 29 countries on an Illumina HiSeq sequencer. Serotype, multilocus ST and antibiotic resista...read more

Mentioned in this Paper

TET1 gene
Capsular
Disseminated
Exfoliation Syndrome
Resistance Process
Clone
Pneumococcal conjugate vaccine
Mitotic DNA Replication Checkpoint
Isolate - Microorganism
Antiretroviral Therapy
1
1
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A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

The Journal of Antimicrobial Chemotherapy

Dec 4, 2019

Stephanie W LoGlobal Pneumococcal Sequencing Consortium

PMID: 31789384

DOI: 10.1093/jac/dkz477

Abstract

We reported tet(S/M) in Streptococcus pneumoniae and investigated its temporal spread in relation to nationwide clinical interventions. We whole-genome sequenced 12 254 pneumococcal isolates from 29 countries on an Illumina HiSeq sequencer. Serotype, multilocus ST and antibiotic resista...read more

Mentioned in this Paper

TET1 gene
Capsular
Disseminated
Exfoliation Syndrome
Resistance Process
Clone
Pneumococcal conjugate vaccine
Mitotic DNA Replication Checkpoint
Isolate - Microorganism
Antiretroviral Therapy
1
1

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