A multi-dimensional approach for describing internal bleeding in an artery: implications for Doppler ultrasound guiding HIFU hemostasis

Physics in Medicine and Biology
Di YangXingbo Fei

Abstract

Doppler ultrasound has shown promise in detecting and localizing internal bleeding. A mathematical approach was developed to describe the internal bleeding of the injured artery surrounded by tissue. This approach consisted of a two-dimensional (2D) model describing the injured vessel and a one-dimensional model (1D) mimicking the downstream of the vessel system. The validity of this approach was confirmed by both the numerical simulation and in vivo measurement of a normal porcine femoral artery. Furthermore, the artery was injured using a 16-gauge needle to model a penetrating injury. The velocity waveform at the puncture site was modeled and compared with those at the upstream and downstream of the artery. The results demonstrated that there was a significant increase in magnitude and a phase lag for the peak systolic velocity at the injury site. These results were qualitatively in agreement with the in vivo experiment. Flow turbulence indicated by this approach was also observed in a color Doppler image in the form of a checkered color pattern. This approach might be useful for quantitative internal bleeding detection and localization. Also, the phase lag of the peak systolic velocity was indicated to be potential in the ap...Continue Reading

References

Oct 1, 1989·Clinical Science·R D EvansD H Williamson
Aug 1, 1989·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·D H EvansM I Levene
Dec 1, 1993·Cell Adhesion and Communication·M ZavortinkD L Brower
Nov 1, 1993·Journal of Biomechanical Engineering·K B Chandran
Jan 1, 1997·Ultrasound in Medicine & Biology·S VaezyL Crum
Sep 18, 1998·Ultrasound in Medicine & Biology·S VaezyL Crum
Dec 16, 1998·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·T DushnitskyS Strauss
Jan 14, 1999·The American Journal of Physiology·N StergiopulosN Westerhof
Aug 26, 1999·Ultrasound in Medicine & Biology·R W MartinL Crum
May 12, 2000·The Journal of the American Association of Gynecologic Laparoscopists·M Y ChangY K Soong
Sep 19, 2002·VASA. Zeitschrift für Gefässkrankheiten·H J KruseS M Schellong
Mar 15, 2006·The Journal of Trauma·Kenji InabaJoseph DuBose
May 1, 2007·Ultrasound in Medicine & Biology·Robyn GreabyShahram Vaezy
Jul 25, 2007·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Wenbo LuoShahram Vaezy
Oct 5, 1987·Biotechnology and Bioengineering·G BeldmanA G Voragen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.