A multi-site study of women living with HIV's perceived barriers to, and interest in, long-acting injectable anti-retroviral therapy

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Morgan M PhilbinLisa R Metsch

Abstract

Adherence to antiretroviral therapy (ART) is imperative for viral suppression and reducing HIV transmission, but many people living with HIV report difficultly sustaining long-term adherence. Long-acting injectable (LAI) ART has the potential to transform HIV treatment and prevention. However, little LAI ART-related behavioral research has occurred among women, particularly outside of clinical trials. Six Women's Interagency HIV Study (WIHS) sites: New York, Chicago, Washington DC, Atlanta, Chapel Hill, and San Francisco. We conducted 59 in-depth interviews with women living with HIV across six WIHS sites (10 per site; 9 at Washington DC). We interviewed women were who were not included in LAI ART clinical trials, but who receive care at university settings that will administer LAI ART once it is approved. Interviews were recorded, transcribed, and analyzed using thematic content analysis. Most women enthusiastically endorsed monthly LAI ART and would prefer it over pills. Three reasons emerged for this preference: 1) convenience and confidentiality; 2) avoiding daily reminders about living with HIV; and 3) believing that shots are more effective than pills. Challenges remain, however, specifically around: 1) medical mistrust; ...Continue Reading

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Citations

Apr 28, 2021·Journal of the International Association of Providers of AIDS Care·Kimberly K Scarsi, Susan Swindells

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