A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico)

Marine Environmental Research
M Cristina FossiLetizia Marsili

Abstract

The main objective of this study was to apply a set of sensitive non-lethal biomarkers in skin biopsies of fin whales (Balaenoptera physalus) to evaluate the toxicological status of this mysticete in the Pelagos Sanctuary (Mediterranean Sea) and in the Gulf of California (Sea of Cortez-Mexico). We developed a "multi-trial diagnostic tool" (based on field and in vitro studies), combining molecular biomarkers (western blot of CYP1A1, CYP2B) and gene expression (qRT-PCR of HSP70, ERα, AHR, E2F-1) with the analysis of OCs, PAHs and PBDEs. The study revealed a higher level of toxicological stress in the Mediterranean fin whales.

References

Apr 2, 2004·Toxicological Sciences : an Official Journal of the Society of Toxicology·Céline A J GodardJohn J Stegeman
Jun 19, 2008·Archives of Environmental Contamination and Toxicology·Carlos Alberto Niño-TorresGina M Ylitalo

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Citations

Jul 11, 2013·BMC Research Notes·Laura M Martinez-LevasseurKarina Acevedo-Whitehouse
Feb 11, 2014·Environmental Science and Pollution Research International·M C FossiR J Urban
Apr 13, 2012·Marine Environmental Research·Maria Cristina FossiMichael H Depledge
Dec 8, 2015·Environmental Pollution·Maria Cristina FossiCristina Panti
Mar 19, 2014·The Science of the Total Environment·Mariana B AlonsoOlaf Malm
Mar 14, 2021·Scientific Reports·Marianna MarangiClaudio Zaccone
Jul 17, 2021·Marine Pollution Bulletin·Rafael André LourençoMárcia Caruso Bícego

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