A multicenter retrospective comparison of goniotomy versus trabecular bypass device implantation in glaucoma patients undergoing cataract extraction

Clinical Ophthalmology
Syril K DorairajInder P Singh

Abstract

The aim of this study was to compare intraocular pressure (IOP) outcomes in eyes with cataract and glaucoma undergoing phacoemulsification (phaco) in combination with goniotomy using the Kahook Dual Blade (KDB) or implantation of a single iStent trabecular bypass device. Retrospective analysis of IOP and IOP-lowering medication reduction in eyes undergoing phaco-goniotomy with KDB (n=237) or phaco-iStent (n=198). Preoperative, intraoperative, and postoperative data were collected through 6 months of follow-up. Outcome measures included mean IOP reduction, mean reduction in IOP-lowering medications, and the proportion of eyes achieving ≥20% IOP reduction or ≥1 medication reduction from baseline. Mean IOP in the phaco-goniotomy with KDB group decreased from 17.9±4.4 mmHg at baseline to 13.6±2.7 mmHg at Month 6 (P<0.001), with mean medication use decreasing from 1.7±0.9 to 0.6±1.0 (P<0.001). In the phaco-iStent group, mean IOP decreased from 16.7±4.4 mmHg to 13.9±2.7 mmHg (P<0.001), with mean IOP-lowering medication use decreasing from 1.9±0.9 to 1.0±1.0 (P<0.001). Mean IOP reduction from baseline was significantly greater in the phaco-goniotomy with KDB group at Month 6 (phaco-goniotomy with KDB -4.2 mmHg [23.7%] vs phaco-iStent ...Continue Reading

Citations

Jun 13, 2019·Journal of Glaucoma·Victoria J MillerMina B Pantcheva
Sep 17, 2020·Annual Review of Vision Science·David J Mathew, Yvonne M Buys
Sep 25, 2020·European Journal of Ophthalmology·Andrew SwiftPatrick Gooi
Jan 16, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C van Oterendorp, D Bahlmann
Jul 23, 2020·Clinical Ophthalmology·Mohammed K ElMallahGabriel S Lazcano-Gomez
Jun 6, 2020·Asia-Pacific Journal of Ophthalmology·Kevin Gillmann, Kaweh Mansouri
Jun 3, 2020·Journal of Cataract and Refractive Surgery·Susan M WakilHenry Tseng
Jul 14, 2020·Journal of Cataract and Refractive Surgery·Steven R SarkisianUNKNOWN ASCRS Glaucoma Clinical Committee
Dec 15, 2020·Current Opinion in Ophthalmology·Kateki Vinod, Steven J Gedde
Feb 20, 2021·Clinical Ophthalmology·Thorsteinn S Arnljots, Mario A Economou
Mar 7, 2021·Journal of Clinical Medicine·Masaki TanitoYotaro Matsuoka
Jul 24, 2021·Seminars in Ophthalmology·Faith A BirnbaumDavid Solá-Del Valle
Dec 23, 2021·Ophthalmology·Steven J GeddeUNKNOWN American Academy of Ophthalmology Preferred Practice Pattern Glaucoma Panel

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