A multicenter study of risk factors and outcome of hospitalized patients with infections due to carbapenem-resistant Acinetobacter baumannii

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Wang-Huei ShengShan-Chwen Chang

Abstract

Risk factors and outcome in patients who acquire nosocomial infections due to carbapenem-resistant Acinetobacter baumannii (CRAB) are rarely investigated. A multicenter retrospective study was conducted to analyze the clinical and microbiological data of patients with nosocomial infections due to A. baumannii in 10 hospitals around Taiwan from May 2004 to December 2006. Comparisons were made between patients with infections due to CRAB and patients with infections due to carbapenem-susceptible A. baumannii (CSAB). One hundred and twenty-one patients carrying CRAB (infections, n=91) and 127 patients carrying CSAB (infections, n=97) were recruited for analysis. Compared with patients with CSAB infections, patients with CRAB infections had a longer duration of hospital stay before A. baumannii was isolated (median 48 vs. 21 days, p<0.001) and were more likely to have had exposure to a carbapenem (adjusted odds ratio (AOR) 2.57, 95% confidence interval (95% CI) 1.43-5.35; p=0.02) and an intensive care unit (ICU) stay (AOR 3.42, 95% CI 1.76-5.26; p=0.008). Risk factors associated with CRAB bacteremia included duration of hospital stay before onset of bacteremia (AOR 1.009 per 1-day longer, 95% CI 1.03-1.24; p=0.049), prior colonizat...Continue Reading

References

Jun 1, 1988·American Journal of Infection Control·J S GarnerJ M Hughes
Jun 18, 1998·The Journal of Antimicrobial Chemotherapy·M Afzal-Shah, D M Livermore
Jul 29, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·V M ManikalJ Quale
Feb 24, 2001·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·L FierobeJ M Desmonts
Feb 2, 2002·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·P R HsuehK T Luh
Jun 8, 2002·Burns : Journal of the International Society for Burn Injuries·Ting Hway WongColin Song
Jul 10, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P J TurnerUNKNOWN MYSTIC Study Group (Europe)
Nov 3, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jesús Rodríguez-BañoUNKNOWN Grupo de Estudio de Infección Hospitalaria (GEIH)
Mar 8, 2005·The Journal of Hospital Infection·E AkinciA Erbay
Mar 24, 2005·Intensive Care Medicine·José Garnacho-MonteroF J Jiménez-Jiménez
Oct 12, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J M CisnerosUNKNOWN Spanish Group for Nosocomial Infection (GEIH) for the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIM
Jan 11, 2007·The Journal of Antimicrobial Chemotherapy·Ki Tae KwonNam Yong Lee
May 22, 2007·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Gülseren BaranMustafa A Cevik
Jul 31, 2007·Diagnostic Microbiology and Infectious Disease·Yu-Chen TsengShan-Chwen Chang
Sep 14, 2007·International Journal of Antimicrobial Agents·Petros KopteridesMatthew E Falagas
Feb 20, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D W WarehamM Millar
Mar 25, 2008·International Journal of Antimicrobial Agents·Lu-Cheng KuoPo-Ren Hsueh
Feb 1, 1993·International Journal of Antimicrobial Agents·R PatonS G Amyes

❮ Previous
Next ❯

Citations

May 9, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H-Y TsaiP-R Hsueh
Dec 15, 2012·BMC Infectious Diseases·Erika Ferraz de GouvêaGuilherme Santoro-Lopes
Aug 2, 2013·Future Microbiology·Christopher Bogan, Dror Marchaim
Oct 2, 2013·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Mohan GurjarRatender Kumar Singh
May 28, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Ying LiMinggui Wang
May 7, 2013·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Lei HuangChang-Phone Fung
May 12, 2012·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Shih-Tse HuangChang-Phone Fung
Dec 3, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hsiu-Mei WeiKao-Pin Hwang
Mar 17, 2015·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Yu-Hsun ChangLih-Shinn Wang
Nov 15, 2011·Medicina clínica·Miguel Gobernado Serrano
Jun 10, 2015·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hao-Yuan LeeCheng-Hsun Chiu
Jan 3, 2015·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Chang-Pan LiuTsong-Rong Yan
Oct 7, 2015·Intensive Care Medicine·José Garnacho-MonteroUNKNOWN European Society of Intensive Care Medicine
Feb 8, 2014·Current Eye Research·Deepa TalrejaAshok Kumar
Dec 17, 2014·Expert Opinion on Pharmacotherapy·Abrar K ThabitDavid P Nicolau
Jun 10, 2015·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hao-Yuan LeeCheng-Hsun Chiu
Oct 18, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·E V LemosK Kawai
Jul 3, 2013·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Faruk EkinciIlker Günay
Aug 18, 2012·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Warunee PunpanichPiyarat Suntarattiwong
May 15, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·E V LemosK Kawai
Sep 23, 2016·The Korean Journal of Internal Medicine·Seong Yeol RyuHyun Ah Kim
Oct 27, 2015·Pharmacotherapy·Keith S Kaye, Jason M Pogue
Feb 18, 2016·Antimicrobial Agents and Chemotherapy·Ruthy Tal-JasperDror Marchaim
Dec 25, 2015·Journal of Clinical Microbiology·Margaret A FitzpatrickAlan R Hauser
Jan 8, 2014·Infection & chemotherapy·Se Yoon ParkMin Huok Jeon
Nov 23, 2013·Infection & chemotherapy·Cheol-In Kang, Jae-Hoon Song
Nov 14, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kai ZhouChao Zhuo
Feb 23, 2013·Expert Review of Anti-infective Therapy·Matthew E FalagasKonstantinos Z Vardakas
Dec 20, 2012·The Pediatric Infectious Disease Journal·Helena C MaltezouMaria Theodoridou
Oct 16, 2019·The Journal of International Medical Research·So Yeon ParkJin Seo Lee
Sep 5, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·François LabasteBernard Georges

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Acinetobacter Infections

Acinetobacter infections have become common in hospitalized patients, especially in the intensive care unit setting and are difficult to treat due to their propensity to develop antimicrobial drug resistance. Discover the latest research on Acinetobacter Infections here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.