PMID: 7547042Sep 1, 1995Paper

A multifactorial analysis to explain inadequate surgical analgesia after extradural block

British Journal of Anaesthesia
M CuratoloF S Venuti

Abstract

A multivariate analysis of inadequate extradural analgesia was carried out prospectively on 1051 patients undergoing lumbar extradural anaesthesia for surgery performed on structures innervated by T10-S5. Ninety-six patients (9%) experienced pain during surgery. Age, extradural fentanyl, diazepam sedation and duration of surgery had no significant influence. We found some weak evidence that the type of surgery affects the risk of feeling pain. The probability of pain increased with increasing weight, except in overweight women, and was significantly greater for both shorter and taller patients, relative to patients of average height. The probability of pain decreased with increasing dose of local anaesthetic, increasing spread of extradural analgesia, addition of adrenaline, and fentanyl or thiopentone sedation. In conclusion, patient-, surgery- and anaesthesia-related factors influence the risk of inadequate extradural analgesia. If such factors are taken into account, an increase in the success rate may be anticipated.

Citations

Oct 30, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·G Le CoqD Benhamou
Dec 3, 2008·International Journal of Obstetric Anesthesia·R AgaramV Gunka
Apr 18, 2003·Anesthesiology Clinics of North America·Dmitry Portnoy, Rakesh B Vadhera
Oct 8, 2014·Veterinary Anaesthesia and Analgesia·Diego SarottiPaolo Franci
Aug 28, 2014·PloS One·Cihun-Siyong Alex GongChien-Kun Ting
Feb 3, 2005·British Medical Bulletin·Michele CuratoloLars Arendt-Nielsen
Jul 1, 2010·Optics Express·Chien-Kun Ting, Yin Chang
Nov 1, 1996·Anesthesia and Analgesia·M CuratoloA M Zbinden
Jan 8, 2019·F1000Research·Carlos DelgadoLaurent A Bollag
Mar 19, 2003·Paediatric Anaesthesia·Lakshmi VasHema Bagry
Jul 1, 2004·The British Journal of Surgery·R J FotiadisT G Allen-Mersh

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