A multiphase method for estimating cohort effects in age-period contingency table data.

Annals of Epidemiology
Katherine M Keyes, Guohua Li

Abstract

Understanding the effects of age, period, and cohort on disease morbidity and mortality may help identify etiological factors and inform prevention programs. We illustrate a three-phase method that conceptualizes the cohort effect as a partial interaction between age and period. As an example of application, we analyze homicide mortality data for males in the United States from 1935 through 2004. The three-phased method begins with graphical inspection; second, a median polish is used to remove the log-additive components of age and period effects; third, a linear regression of residuals from the median polish is modeled to quantify the relative magnitude of the cohort effect. Individuals born after 1960 have a significantly increased rate of homicide relative to those born between 1920 and 1924. After removal of the log-additive effects of age and period, the estimated homicide rate for men born between 1980 and 1984 is more than twice the rate for men born between 1920 and 1924 (rate ratio, 2.11; 95% confidence interval, 1.98-2.25). The three-phase method presented herein offers several advantages, the foremost being an alternative conceptualization of the cohort effect not as an independent component of age and period effect...Continue Reading

References

Jan 1, 1992·Statistical Methods in Medical Research·T R Holford
Jun 1, 1987·Statistics in Medicine·D Clayton, E Schifflers
Jun 1, 1987·Statistics in Medicine·D Clayton, E Schifflers
Sep 1, 1986·Statistics in Medicine·C Robertson, P Boyle
Mar 1, 1985·International Journal of Epidemiology·G Rose
Dec 1, 1965·American Sociological Review·N B Ryder
Jan 1, 1996·American Journal of Epidemiology·R E Tarone, K C Chu
Feb 15, 1996·Statistics in Medicine·W C Lee, R S Lin
Dec 10, 1999·American Journal of Epidemiology·C Shahpar, G Li
Oct 20, 2001·AJS; American Journal of Sociology·R M O'BrienL Isaacson
Aug 1, 1965·Psychological Bulletin·K W SCHAIE
Apr 27, 2005·American Journal of Human Genetics·Laura S SchmidtW Marston Linehan

❮ Previous
Next ❯

Citations

Dec 12, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·W R RobinsonY Yang
May 2, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·W R RobinsonY Yang
Apr 2, 2016·Proceedings of the National Academy of Sciences of the United States of America·Rune Lindahl-JacobsenJames W Vaupel
Dec 28, 2010·Seizure : the Journal of the British Epilepsy Association·Ya-Hui ChangTsung-Hsueh Lu
Feb 26, 2013·Drug and Alcohol Dependence·Katherine M Keyes, Richard Miech
Aug 23, 2016·Injury Epidemiology·Victor Puac-PolancoGuohua Li
May 24, 2014·International Journal of Geriatric Psychiatry·Yu-Tzu WuCarol Brayne
Aug 11, 2015·Journal of Epidemiology·Tetsuji TondaKen-ichi Kamo
Nov 20, 2019·Journal of the National Cancer Institute·Ashish A DeshmukhKeith Sigel
Sep 2, 2020·Biometrical Journal. Biometrische Zeitschrift·Tatjana Miljkovic, Xin Wang
Dec 11, 2019·International Journal of Environmental Research and Public Health·I-Shiang TzengWen-Shan Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.