A multiwire microelectrode for single unit recording in deep brain structures

Journal of Neuroscience Methods
D JaegerJ W Aldridge

Abstract

A method is described by which a single shaft multiwire microelectrode can be fabricated efficiently. The resulting electrode can be attached to a commercial microdrive and used for single neuronal unit recording from one or more tracks in deep brain structures of anesthetized or awake animals. The electrode consists of a 30 gauge stainless steel cannula through which multiple strands of 13 micron insulated tungsten microwires are threaded. At the electrode tip the wires protrude 3-4 mm from the cannula and are cut individually at suitable offsets. The tip is stabilized and fixed to the cannula with cyanoacrylate. At the base of the electrode the wires are threaded through flexible plastic tubing that provides strain relief and are glued to individual pins of a miniature connector that plugs into a field effect transistor (FET) voltage follower. Good single unit recordings have been obtained routinely from the basal ganglia of awake, behaving monkeys with this electrode.

References

Jun 1, 1977·Physiology & Behavior·H EichenbaumS L Chorover
Jun 1, 1986·Journal of Neuroscience Methods·J A Kaltenbach, G L Gerstein
Oct 1, 1972·Physiology & Behavior·S L Chorover, A M DeLuca
Jan 1, 1983·Experimental Brain Research·A MichalskiR Tarnecki
Nov 1, 1982·Journal of Neuroscience Methods·J Krüger
Jan 1, 1981·Experimental Brain Research·J Krüger, M Bach

❮ Previous
Next ❯

Citations

Dec 1, 1995·Journal of Neuroscience Methods·G E LoebJ Martyniuk
Feb 13, 2001·Journal of Neuroscience Methods·I SzabóG Buzsáki
May 1, 1999·Journal of Neuroscience Methods·P J Rousche, R A Normann
Jul 16, 2008·Journal of Neuroscience Methods·Helen Sherk, Elizabeth J Wilkinson
Nov 26, 2008·Biosensors & Bioelectronics·Chang-Hsiao ChenShih-Rung Yeh
Dec 24, 1997·IEEE Transactions on Bio-medical Engineering·K E Jones, R A Normann
May 13, 2005·IEEE Transactions on Bio-medical Engineering·Paulo S Motta, Jack W Judy
Dec 1, 2015·Behavioural Brain Research·Christy A ItogaJ Wayne Aldridge
Feb 21, 1994·Brain Research·C T NordhausenR A Normann
Aug 4, 2006·Journal of Neurophysiology·Amy J TindellJ Wayne Aldridge
Dec 23, 2017·Frontiers in Neuroscience·Katarzyna M SzostakTimothy G Constandinou
Apr 1, 2008·The International Journal of Artificial Organs·G PeraleM Masi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Basal Forebrain & Food Avoidance

Neurons in the basal forebrain play specific roles in regulating feeding. Here are the latest discoveries pertaining to the basal forebrain and food avoidance.

Related Papers

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Jong Seok BaeByoung Joon Kim
The European Journal of Neuroscience
Elizabeth J WilkinsonHelen Sherk
© 2021 Meta ULC. All rights reserved