A mycobacterial disease is associated with the silent mass mortality of the pen shell Pinna nobilis along the Tyrrhenian coastline of Italy

Scientific Reports
F CarellaG De Vico

Abstract

Disease is an increasing threat for marine bivalves worldwide. Recently, a mass mortality event (MME) impacting the bivalve Pinna nobilis was detected across a wide geographical area of the Spanish Mediterranean Sea and linked to a haplosporidian parasite. In 2017-2018, mass mortality events affecting the pen shell Pinna nobilis were recorded in two different regions of Italy, Campania and Sicily, in the Tyrrhenian Sea (Mediterranean Sea). Histopathological and molecular examinations of specimens showed the presence of Haplosporidium sp. in only one specimen in one area. Conversely, in all of the surveyed moribund animals, strong inflammatory lesions at the level of connective tissue surrounding the digestive system and gonads and linked to the presence of intracellular Zhiel-Neelsen-positive bacteria were observed. Molecular analysis of all of the diseased specimens (13) confirmed the presence of a Mycobacterium. Blast analysis of the sequences from all of the areas revealed that they were grouped together with the human mycobacterium M. sherrisii close to the group including M. shigaense, M. lentiflavum and M. simiae. Based on pathological and molecular findings, it is proposed that a mycobacterial disease is associated with ...Continue Reading

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Citations

Aug 7, 2019·Zoonoses and Public Health·Gionata De Vico, Francesca Carella
Aug 14, 2020·Environmental Monitoring and Assessment·Željko PavlinecSnježana Zrnčić
Dec 11, 2020·Marine Environmental Research·Patricia PradoJosé Rafael García-March
Dec 29, 2020·Journal of Invertebrate Pathology·Charlotte E Davies
Apr 27, 2021·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·İbrahim Ender KüniliUğur Altinağaç
Feb 4, 2022·Molecular Biology Reports·Gaetano CataneseRobert Bunet

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Datasets Mentioned

BETA
MH572222

Methods Mentioned

BETA
dissection
PCR
Electron
electron microscopy
light microscopy

Software Mentioned

BLAST
ClustalW
MEGA X
BLASTN

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