A mycotoxin-deactivating feed additive counteracts the adverse effects of regular levels of Fusarium mycotoxins in dairy cows.

Journal of Dairy Science
A GalloE Trevisi

Abstract

Little is known about the effects of commonly found levels of Fusarium mycotoxins on the performance, metabolism, and immunity of dairy cattle. We investigated the effects of regular contamination levels, meaning contamination levels that can be commonly detected in dairy feeds, of deoxynivalenol (DON) and fumonisins (FB) in total mixed ration (TMR) on the performance, diet digestibility, milk quality, and plasma liver enzymes in dairy cows. This trial examined 12 lactating Holstein dairy cows using a 3-period × 3-treatment Latin square design. The experimental period was 21 d of mycotoxin exposure followed by 14 d of washout. During treatment periods, cows received one of 3 diets: (1) CTR (control) diet of TMR contaminated with 340.5 µg of DON/kg of dry matter (DM) and 127.9 µg FB/kg of DM; (2) MTX diet of TMR contaminated with Fusarium mycotoxins at levels higher than CTR but below US and European Union guidelines (i.e., 733.0 µg of DON/kg of DM and 994.4 µg of FB/kg of DM); or (3) MDP diet, which was MTX diet supplemented with a mycotoxin deactivator product (i.e., 897.3 µg of DON/kg of DM and 1,247.1 µg of FB/kg of DM; Mycofix, 35 g/animal per day). During washout, all animals were fed the same CTR diet. Body weight, body c...Continue Reading

References

Mar 1, 1982·The Journal of Investigative Dermatology·P P BradleyG Rothstein
Apr 1, 1993·Journal of Dairy Science·R L Ireland-Perry, C C Stallings
May 15, 1998·Journal of Animal Science·R C LittellC B Ammerman
Apr 6, 2000·Journal of Dairy Science·K A BeaucheminR Kampen
Oct 3, 2000·Veterinary Research Communications·F CaloniG Pompa
Nov 23, 2000·Journal of Agricultural and Food Chemistry·A E Desjardins, R D Plattner
Jul 2, 2004·Nature Reviews. Immunology·Shizuo Akira, Kiyoshi Takeda
May 17, 2006·Journal of Dairy Science·S SeoD G Fox
Oct 19, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Abdellah ZinedineJordi Mañes
Nov 10, 2006·Critical Reviews in Food Science and Nutrition·Bulent KabakIşil Var
Apr 25, 2007·Food Additives and Contaminants·Judit FodorMelinda Kovacs
Jul 20, 2007·Journal of Dairy Science·S N KorostelevaH J Boermans
Feb 21, 2008·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Johanna Fink-Gremmels
Mar 18, 2008·The Veterinary Journal·J Fink-Gremmels
Feb 25, 2009·Nucleic Acids Research·J M RuijterA F M Moorman
Sep 15, 2009·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·A GalloA Pietri
Nov 20, 2009·Journal of Biotechnology·Stefan HeinlReingard Grabherr
Jan 25, 2011·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Umberto BernabucciBruno Ronchi
Sep 25, 2012·The Journal of Dairy Research·Denis PrettoMartino Cassandro
Oct 2, 2012·Journal of Dairy Science·G BittanteA Cecchinato
Jun 14, 2013·Journal of Agricultural and Food Chemistry·Bertrand GrenierIsabelle P Oswald
Dec 24, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Janine WinklerSven Dänicke
May 23, 2014·Food Additives & Contaminants. Part B, Surveillance·Terenzio BertuzziAmedeo Pietri
Dec 6, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Irene HahnFranz Berthiller
Mar 11, 2016·The Journal of Toxicological Sciences·Kei-ichi SugiyamaKen-ichi Tanamoto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.