A nano silver-xerogel (Ag nps@modified TEOS) as a newly developed nanocatalyst in the synthesis of benzopyranopyrimidines (with secondary and primary amines) and gem-bisamides

Dalton Transactions : an International Journal of Inorganic Chemistry
Gurpreet Kour, Monika Gupta

Abstract

Silver nanoparticles have been prepared from a chemical reduction approach and supported on modified TEOS (tetraethylorthosilicate) xerogels to be studied as a nanocatalyst in the conversions of benzopyranopyrimidines (with primary as well as secondary amines along with the mechanism by trapping the imine intermediate) and also in the synthesis of gem-bisamides. Different conditions for the performance of the nanocatalyst have been screened and tolerance with respect to variable functionalities has been observed, resulting in excellent yields; and confirmation of products synthesized has been done using studies like1H NMR,13C NMR and mass analysis. Also, SEM-EDX and TEM of the nanocatalyst have been performed to know the internal and external morphology, size and elemental composition. UV and XRD analysis to confirm the silver nanoparticles' and xerogel's presence, TGA to study the thermal stability and FTIR to study the modification pattern of the nanocatalyst have been undertaken and presented in this work.

References

Jul 8, 2000·Anti-cancer Drugs·J A HadfieldA T McGown
May 6, 2009·Expert Opinion on Drug Delivery·David Quintanar-GuerreroElizabeth Piñón-Segundo
May 7, 2010·Journal of the American Chemical Society·Huan CongJohn A Porco
Jan 3, 2013·Journal of Chemical Information and Modeling·Chao MaXiang-Qun Xie

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