A Narrative Review of Where We Are With Point-of-Care Sexually Transmitted Infection Testing in the United States.

Sexually Transmitted Diseases
Charlotte A GaydosJohan H Melendez

Abstract

Point-of-care (POC) tests enable immediate diagnosis and targeted treatment of sexually transmitted infections (STIs), which could accelerate control of ongoing epidemics. Although older nucleic acid amplification tests have improved the accuracy of laboratory-based tests for STIs, newer POC tests can facilitate control efforts. We sought to review the performance and time to result of POC assays for STIs in the last 10 years. The authors performed a PubMed, US National Library of Medicine, National Center for Biotechnology Information search for POC tests for STIs or sexually transmitted diseases. Diagnostic technology for POC assays for STIs has achieved high sensitivity and specificity (>90%) using recent molecular advances in the last 10 years. Three POC tests for chlamydia and gonorrhea and 2 for trichomonas have been cleared by the Food and Drug Administration and can provide rapid results during the clinical encounter. Two POC assays for syphilis are now cleared by the Food and Drug Administration. Other similar POC assays are in development. These "fast followers" have faster time to result and will extend the diagnostic armamentarium at POC. New technology has improved the performance accuracy of STI POC diagnostics. I...Continue Reading

References

Apr 20, 2010·Point of Care·Jill HuppertCharlotte A Gaydos
Mar 8, 2013·Journal of Clinical Microbiology·Charlotte A GaydosUNKNOWN CT/NG Study Group
Oct 29, 2013·Sexual Health·Anne M RompaloCharlotte A Gaydos
Feb 4, 2014·Expert Review of Anti-infective Therapy·Charlotte Gaydos, Justin Hardick
Jun 20, 2018·Sexual Health·Anne M RompaloCharlotte A Gaydos
Aug 15, 2018·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S G BadmanA Kelly-Hanku
Nov 21, 2018·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Susanne JacobssonMagnus Unemo
Dec 20, 2019·Sexually Transmitted Diseases·Jesse GettingerBarbara Van Der Pol
May 15, 2020·JAMA Network Open·Barbara Van Der PolCharlotte A Gaydos
Jun 6, 2020·Expert Review of Molecular Diagnostics·Charlotte A Gaydos, Johan H Melendez

❮ Previous
Next ❯

Citations

May 11, 2021·Sexually Transmitted Diseases·Brian H RaphaelVirginia B Bowen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.