PMID: 3214466Aug 1, 1988Paper

A nation-wide study of atherosclerosis in infants, children and young adults in Japan

Atherosclerosis
K TanakaY Nishiyama

Abstract

This paper reports the results of a nation-wide cooperative study of atherosclerosis in young, first generation Japanese with ages ranging from 1 month to 39 years, who were autopsied between 1978 and 1982 in hospitals distributed over the entire archipelago of Japan. Atherosclerotic lesions in 2320 aortas, 1620 coronary arteries and 344 cerebral arteries were classified into fatty streaks, fibrous plaques and complicated lesions and were then quantificated with the point-counting method. Atherosclerosis of aortas, coronary arteries and cerebral arteries, determined by surface involvement (SI) of atherosclerotic lesions and atherosclerotic index (AI), increased with age; the severest were seen in aortas, and then, with decreasing severity, in the coronary and cerebral arteries. Fatty streaks preceded the other lesions and accounted for the largest portion of the lesions in aortas and coronary arteries. Fibrous plaques and complicated lesions developed in the later decades of life. The patients with collagen diseases had a greater severity of aortic atherosclerosis in the 2nd and 3rd decades of life, than those without such disorders. Correlation of antemortem clinical data with SI and AI of each artery were analyzed, using simp...Continue Reading

References

Jul 1, 1979·Stroke; a Journal of Cerebral Circulation·S SadoshimaK Tanaka
Jan 16, 1986·The New England Journal of Medicine·C J Glueck
Apr 12, 1985·JAMA : the Journal of the American Medical Association
Sep 1, 1972·Atherosclerosis·L A Solberg, P A McGarry
May 1, 1969·Circulation·A B BakerR B Loewenson
Feb 1, 1982·The American Journal of Cardiology·C J HomcyL M Miller
Jul 1, 1981·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·I HolmeJ P Strong
May 1, 1980·Atherosclerosis·S SadoshimaS Katsuki
Sep 1, 1962·The American Journal of Cardiology·I GOREP D WHITE
Mar 1, 1965·Journal of Atherosclerosis Research·J R MITCHELL, W I CRANSTON

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Citations

May 19, 2000·Experimental Gerontology·P D ReavenJ L Witztumc
Nov 8, 2002·Pediatrics International : Official Journal of the Japan Pediatric Society·Tomoo OkadaKensuke Harada
Aug 1, 1993·Acta Paediatrica Japonica; Overseas Edition·T OhjiM Yamagishi
Feb 1, 1996·Acta Paediatrica Japonica; Overseas Edition·J FukushigeY Nose
May 1, 1996·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·O JärvinenM Tarkka
Jan 1, 1990·Annals of the New York Academy of Sciences·K SueishiK Tanaka
Jan 1, 1990·Annals of the New York Academy of Sciences·K Tanaka
Jan 1, 1990·Annals of the New York Academy of Sciences·I SakuraiT Sawada
Dec 1, 1994·Postgraduate Medical Journal·S R MaxwellM J Kendall
Jun 6, 2009·Pathology, Research and Practice·Yutaka NakashimaKatsuo Sueishi
Mar 25, 2011·Diabetes/metabolism Research and Reviews·Cosimo GianniniC J H Kelnar
Apr 13, 2005·Atherosclerosis·Hidehiro TakeiGray T Malcom
Oct 8, 2009·Pediatrics International : Official Journal of the Japan Pediatric Society·Ying LiaoJunbao Du
Jan 27, 2015·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Thomas G BeachMarwan N Sabbagh
Jan 1, 2004·Clinical Pediatric Endocrinology : Case Reports and Clinical Investigations : Official Journal of the Japanese Society for Pediatric Endocrinology·Yohei OgawaMakoto Uchiyama
Sep 13, 2002·Journal of Atherosclerosis and Thrombosis·Tsutomu YamadaHiroshige Itakura
Jan 21, 2000·Preventive Medicine·D R Labarthe
Jan 30, 2010·Korean Circulation Journal·Young Mi Hong
May 4, 2016·Journal of cardiology·Mikiko HaradaUNKNOWN Study Project on Prevention of Metabolic Syndrome among Children, Adolescents, and Young Adults in Shinshu
Jul 10, 2004·Journal of Epidemiology·Katsuyasu KoudaHiroichi Takeuchi
Apr 1, 1994·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·M S WolfeL L Rudel
Feb 18, 2006·International Journal of Radiation Biology·Michiko YamadaGen Suzuki
Jun 29, 2000·Journal of Atherosclerosis and Thrombosis·A KisanukiA Sumiyoshi
May 23, 2019·Artificial Cells, Nanomedicine, and Biotechnology·Samira Tabaei, Seyyedeh Samaneh Tabaee
Sep 5, 2014·Science Translational Medicine·Tomasz ZemojtelPeter N Robinson
Nov 10, 2018·Science·Hilary C MartinUNKNOWN Deciphering Developmental Disorders Study
Apr 27, 2019·Journal of Medical Genetics·David BickJohn Belmont
Sep 11, 2019·Cold Spring Harbor Perspectives in Medicine·Alison M Elliott
Apr 16, 2008·International Journal of Clinical Practice·K CefleA Selek
Mar 24, 2009·Human Mutation·Jim KaputUNKNOWN Contributors to the Human Variome Project Planning Meeting

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