A national study of breast and colorectal cancer patients' decision-making for novel personalized medicine genomic diagnostics

Personalized Medicine
Amalia M IssaJohn McKeever

Abstract

Molecular diagnostics are increasingly being used to help guide decision-making for personalized medical treatment of breast and colorectal cancer patients. The main aim of this study was to better understand and determine breast and colorectal cancer patients' decision-making strategies and the trade-offs they make in deciding about characteristics of molecular genomic diagnostics for breast and colorectal cancer. We surveyed a nationally representative sample of 300 breast and colorectal cancer patients using a previously developed web-administered instrument. Eligibility criteria included patients aged 18 years and older with either breast or colorectal cancer. We explored several attributes and attribute levels of molecular genomic diagnostics in 20 scenarios. Our analysis revealed that both breast and colorectal cancer patients weighted the capability of molecular genomic diagnostics to determine the probability of treatment efficacy as being of greater importance than information provided to detect adverse events. The probability of either false-positive or -negative results was ranked highly as a potential barrier by both breast and colorectal patients. However, 78.6% of breast cancer patients ranked the possibility of a...Continue Reading

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Citations

Jul 25, 2018·Parasite : Journal De La Société Française De Parasitologie·Taiwu WangHong Lin
Jul 1, 2014·Personalized Medicine·Gillian BartlettAmalia M Issa
Aug 22, 2017·NPJ Precision Oncology·Fenil ShahMark R Kelley
Jun 5, 2021·The Patient·Semra OzdemirRemee Rose Quintana Ocampo

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