A nationwide case-control study of Escherichia coli O157:H7 infection in the United States

The Journal of Infectious Diseases
L SlutskerP M Griffin

Abstract

Risk factors for Escherichia coli O157:H7 infection were investigated in a case-control study at 10 medical centers throughout the United States. Among 73 case-patients and 142 matched controls, exposures in the 7 days before illness associated with E. coli O157:H7 infection in univariate analysis included consumption of hamburger (matched odds ratio [MOR], 3.8; 95% confidence interval [CI], 1.9-7.9), undercooked hamburger (MOR, 4.5; 95% CI, 1.6-12.2), or hot dogs (MOR, 2.2; 95% CI, 1.1-4.4); eating at a fast-food restaurant (MOR, 2.3; 95% CI, 1.1-4.6); drinking unchlorinated well water (MOR, 2.4; 95% CI, 1.1-5.7); swimming in a pond (MOR, 5.4; 95% CI, 1.1-26.0); and having a household member with diarrhea (MOR, 11.9; 95% CI, 2.7-53.5). In multivariate analysis, only eating undercooked hamburger remained associated with infection. Seven (8%) of 93 patients developed hemolytic uremic syndrome and 1 died. Prevention strategies aimed at modifying risk factors may help to reduce the risk of infection with E. coli O157:H7.

Citations

Aug 16, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Johanna ScheiringLothar Bernd Zimmerhackl
Jul 13, 2004·Current Gastroenterology Reports·J Mark Lawson
Nov 30, 2000·Current Infectious Disease Reports·J L Jaeger, D W Acheson
Aug 31, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S DundasS J Hutchinson
Mar 27, 2012·Foodborne Pathogens and Disease·Kathleen E FullertonUNKNOWN International Collaboration Working Group
Oct 7, 2006·Current Opinion in Gastroenterology·D W Acheson
Jul 6, 2000·Symposium Series·S M Parry, S R Palmer
Jul 6, 2000·Symposium Series·R M ChalmersF J Bolton
May 7, 2003·Applied and Environmental Microbiology·F OmisakinN J C Strachan
Oct 19, 2004·Clinical Microbiology Reviews·Saul TziporiHoward Trachtman
May 11, 2012·Journal of Clinical Microbiology·Alton G SwennesJames G Fox
Dec 4, 2013·BMC Infectious Diseases·Brian A MapongaLucia Takundwa
Jan 24, 2012·BMC Public Health·Hassan VallyPatricia Desmarchelier
Aug 14, 2012·Drug Design, Development and Therapy·Lindsay S KeirJon Jin Kim
Apr 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jennifer M NelsonElaine Scallan
Jul 20, 2014·Advances in Pediatrics·Sabah Kalyoussef, Kristina N Feja
Jan 17, 2012·Medicina intensiva·B BorgattaJ Rello
Aug 10, 1999·Current Problems in Pediatrics·M Noguera-Obenza, T G Cleary
Sep 3, 2004·The Journal of Pediatrics·Ann E SalernoBernard S Kaplan
Dec 1, 2006·Molecular Immunology·Emily StoneJianbing Zhang
Aug 29, 2006·International Journal of Food Microbiology·Norval J C StrachanIain D Ogden
Feb 27, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stephen B FreedmanXiao-Li Pang
Oct 13, 2005·Water Research·Franciska M SchetsAna Maria de Roda Husman
Aug 30, 2005·Current Problems in Pediatric and Adolescent Health Care·Elizabeth Jane Elliott, Roy Michael Robins-Browne
Jun 21, 2015·The Journal of Antimicrobial Chemotherapy·Morten AggerAndreas Munk Petersen
Dec 20, 2007·Acta Microbiologica Et Immunologica Hungarica·S OulkheirB Attarassi
Jun 24, 2015·Antimicrobial Agents and Chemotherapy·Craig SkinnerXiaohua He
Sep 10, 2015·Antimicrobial Agents and Chemotherapy·Jing DongXuming Deng

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