Abstract
The aim of this study was to evaluate a possible association between malignancy and anxiety disorders (AD) in Taiwan. We employed data from the National Health Insurance system of Taiwan. The AD cohort contained 24,066 patients with each patient randomly frequency matched according to age and sex with 4 individuals from the general population without AD. Cox's proportional hazard regression analysis was conducted to estimate the influence of AD on the risk of cancer. Among patients with AD, the overall risk of developing cancer was only 1% higher than among subjects without AD, and the difference was not significant (hazard ratio [HR] = 1.01, 95% confidence interval [95% CI] = 0.95-1.07). With regard to individual types of cancer, the risk of developing prostate cancer among male patients with AD was significantly higher (HR = 1.32, 95% CI = 1.02-1.71). On the other hand, the risk of cervical cancer among female patients with AD was marginally significantly lower than among female subjects without AD (HR = 0.72, 95% CI = 0.51-1.03). One major limitation is the lack of information regarding the life style or behavior of patients in the NHI database, such as smoking and alcohol consumption. Despite the failure to identify a relat...Continue Reading
References
Jan 1, 1991·Psychotherapy and Psychosomatics·A Forsén
Jan 1, 1989·Social Science & Medicine·J Gross
Apr 1, 1989·Acta Psychiatrica Scandinavica·C FaravelliL Giardinelli
Feb 1, 1989·Acta Psychiatrica Scandinavica·H G HwuL Y Chang
Aug 1, 1988·American Heart Journal·T G Pickering, W Gerin
Jan 1, 1982·Social Science & Medicine·T Cox, C Mackay
May 1, 1994·Archives of General Psychiatry·H U WittchenW W Eaton
Feb 1, 1993·Archives of General Psychiatry·C N ChenM Fung
Nov 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A GinsbergE Nottage
Oct 16, 1999·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·M C McKennaJ Rounds
Oct 16, 1999·BMJ : British Medical Journal·D ProtheroeA House
Jun 14, 2000·Psychosomatic Medicine·T RitzM Costa
Mar 29, 2001·International Journal of Cancer. Journal International Du Cancer·K LillbergM Koskenvuo
May 22, 2003·Health Affairs·Jui-Fen Rachel Lu, William C Hsiao
Feb 8, 2005·BMJ : British Medical Journal·Caroline BurgessAmanda Ramirez
Oct 1, 2005·International Review of Psychiatry·George N Papadimitriou, Paul Linkowski
Oct 6, 2005·Journal of Anxiety Disorders·Sandra Baker MorissetteSuzy Bird Gulliver
Dec 14, 2007·Medizinische Klinik·Sabine SchwarzMartina Dören
May 22, 2008·Nature Clinical Practice. Oncology·Yoichi ChidaAndrew Steptoe
Jul 29, 2008·Addictive Behaviors·Sandra B MorissetteDomenic Ciraulo
Feb 24, 2009·Journal of Psychosomatic Research·Mark HamerGerard J Molloy
Oct 27, 2009·Psychosomatics·Linda F Brown, Kurt Kroenke
Dec 10, 2009·Cancer·Brenda K EdwardsLynn A G Ries
Jul 14, 2010·Journal of the American College of Cardiology·Annelieke M RoestJohan Denollet
Nov 3, 2010·BMC Cancer·Nauman A JadoonZeshan S Choudhry
Dec 22, 2010·Diabetology & Metabolic Syndrome·Ali Khan KhuwajaFranklin White
Jan 5, 2011·Rheumatology International·Ji-An LiangChia-Hung Kao
Citations
Mar 6, 2013·PloS One·Cheng-Che ShenChia-Jen Liu
Oct 12, 2013·Pharmacoepidemiology and Drug Safety·Li-Min SunChia-Hung Kao
Feb 18, 2014·Journal of Psychosomatic Research·Siobhan O'NeillKate M Scott
Nov 18, 2016·BMC Urology·Yung-Chan ChenShiu-Dong Chung
Mar 6, 2016·Medicine·Cheng-Che ShenTung-Ping Su
Jun 10, 2016·Medicine·Frank Cheau-Feng LinYung-Po Liaw
Nov 21, 2019·Molecular Psychiatry·Yun-He WangYan-Ping Bao
Feb 13, 2014·Journal of Cancer Research and Clinical Oncology·Chia-Ter ChaoUNKNOWN National Taiwan University Study Group on Acute Renal Failure
Oct 25, 2020·Psycho-oncology·Juan ZhuWenqiang Wei