A near infrared spectroscopy-based test of calf muscle function in patients with peripheral arterial disease

The International Journal of Angiology : Official Publication of the International College of Angiology, Inc
Brian Lindegaard PedersenBjørn Quistorff

Abstract

Background The study aims to test a new, simple, and reliable apparatus and procedure for the diagnostics and treatment evaluation of peripheral arterial disease (PAD). The test apparatus involves near infrared spectroscopy (NIRS) of a main part of the lower leg muscles during isometric flexion and extension of the ankle joint performed with the foot strapped in a specially designed pedal ergometer. Design To evaluate the reproducibility of the new test compared with an existing testing method of treadmill walking. Methods Eleven patients participated in the study: nine patients with claudication and two age-matched patients without claudication. Each patient was tested with an isometric ergometer pedal test and a treadmill test applying NIRS measurements of the anterior tibial and the gastrocnemius muscles (GAS). Tests were repeated three times with randomly selected intervals between individual test runs. Intraclass correlation constant (ICC) was used to describe reproducibility. The ICC was calculated using the area under the NIRS oxygenated hemoglobin (Hbox) curve, the initial velocity of the Hbox recovery curve, force measurements, and walking time. Results The ICC of the GAS was between 0.92-0.95 (foot-pedal) and 0.70-0.9...Continue Reading

Citations

May 22, 2016·Seminars in Cardiothoracic and Vascular Anesthesia·Michael Stuart GreenRayhan Tariq
Jun 3, 2017·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·F ManfrediniP Zamboni
Mar 13, 2019·International Angiology : a Journal of the International Union of Angiology·Frederik L EikenJonas P Eiberg
May 21, 2019·Pacing and Clinical Electrophysiology : PACE·Daniel Robert QuastJuris Jendrik Meier
May 20, 2021·International Angiology : a Journal of the International Union of Angiology·Brian L PedersenBjørn Quistorff

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