A neural circuit for gamma-band coherence across the retinotopic map in mouse visual cortex

ELife
Richard HakimHillel Adesnik

Abstract

Cortical gamma oscillations have been implicated in a variety of cognitive, behavioral, and circuit-level phenomena. However, the circuit mechanisms of gamma-band generation and synchronization across cortical space remain uncertain. Using optogenetic patterned illumination in acute brain slices of mouse visual cortex, we define a circuit composed of layer 2/3 (L2/3) pyramidal cells and somatostatin (SOM) interneurons that phase-locks ensembles across the retinotopic map. The network oscillations generated here emerge from non-periodic stimuli, and are stimulus size-dependent, coherent across cortical space, narrow band (30 Hz), and depend on SOM neuron but not parvalbumin (PV) neuron activity; similar to visually induced gamma oscillations observed in vivo. Gamma oscillations generated in separate cortical locations exhibited high coherence as far apart as 850 μm, and lateral gamma entrainment depended on SOM neuron activity. These data identify a circuit that is sufficient to mediate long-range gamma-band coherence in the primary visual cortex.

References

Mar 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·C M Gray, W Singer
Jan 1, 1995·Annual Review of Neuroscience·W Singer, C M Gray
May 1, 1996·Trends in Neurosciences·J G JefferysM A Whittington
Apr 9, 1999·Nature Neuroscience·A ReyesB Sakmann
Apr 3, 2001·Nature Reviews. Neuroscience·F VarelaJ Martinerie
Aug 3, 2001·Nature Reviews. Neuroscience·E Salinas, T J Sejnowski
Jan 11, 2002·Developmental Biology·T Saito, N Nakatsuji
Jan 28, 2003·Neuron·Jozsef CsicsvariGyörgy Buzsáki
Nov 20, 2003·Trends in Neurosciences·Miles A Whittington, Roger D Traub
Apr 29, 2004·Nature Neuroscience·György Buzsáki
Jun 26, 2004·Science·György Buzsáki, Andreas Draguhn
Sep 21, 2004·Nature Reviews. Neuroscience·Henry MarkramCaizhi Wu
Oct 9, 2004·Progress in Biophysics and Molecular Biology·Edward O Mann, Ole Paulsen
Nov 13, 2004·The Journal of Physiology·Edward O MannOle Paulsen
Aug 12, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael A LongBarry W Connors
Dec 21, 2006·Nature Reviews. Neuroscience·Marlene BartosPeter Jonas
Jan 12, 2007·Journal of Neurophysiology·D GuanR C Foehring
May 23, 2007·Nature Neuroscience·Christoph KapferMassimo Scanziani
Jun 9, 2007·Trends in Neurosciences·Pascal FriesWolf Singer
Jun 16, 2007·Science·Thilo WomelsdorfPascal Fries
Aug 8, 2007·Proceedings of the National Academy of Sciences of the United States of America·Adriano B L TortNancy J Kopell
Apr 28, 2009·Nature·Jessica A CardinChristopher I Moore
Apr 28, 2009·Nature·Vikaas S SohalKarl Deisseroth
Apr 30, 2009·Annual Review of Neuroscience·Pascal Fries
Sep 26, 2009·Neuron·Paul Tiesinga, Terrence J Sejnowski
Nov 20, 2009·Nature·Laura Lee ColginEdvard I Moser
Jan 22, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Gabriel LepousezCécile Viollet
Mar 2, 2010·Neuron·Cristopher M Niell, Michael P Stryker
Apr 24, 2010·Nature·Hillel Adesnik, Massimo Scanziani
Nov 12, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Attila I GulyásNorbert Hájos
Dec 15, 2010·Developmental Neurobiology·Miles A WhittingtonRoger D Traub
May 11, 2011·PLoS Biology·Xiaoxuan Jia, Adam Kohn
Nov 25, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthew AinsworthMiles A Whittington
Dec 22, 2011·Journal of Computational Neuroscience·Martin VinckCyriel Pennartz
Mar 27, 2012·Annual Review of Neuroscience·György Buzsáki, Xiao-Jing Wang
Oct 13, 2012·Nature·Hillel AdesnikMassimo Scanziani

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Citations

Feb 6, 2020·Journal of Neurophysiology·Christoforos A PapasavvasYujiang Wang
Oct 3, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Joana LourençoAlberto Bacci
Apr 6, 2021·Frontiers in Systems Neuroscience·Zijie LiLing Qin

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