A neural connection between the central part of the medial preoptic nucleus and the bed nucleus of the stria terminalis to regulate sexual behavior in male rats

Neuroscience Letters
Sho MaejimaShinji Tsukahara

Abstract

The medial preoptic nucleus (MPN) is a regulatory center for male sexual behavior. It consists of sexually dimorphic structures that are male biased, and these structures are found in the central part of the MPN (MPNc). The bed nucleus of the stria terminalis (BNST) also participates in male sexual behavior, and receives efferent neural projections from the MPNc. In this study, we examined if MPNc neurons projecting to the BNST are activated in male rats displaying sexual behavior. Fluoro-Gold (FG; a retrograde neural tracer) was injected into the BNST of male rats, which were separated into two groups: (1) those in contact with estrous female rats and displayed sexual behavior followed by ejaculation and (2) those without contact with estrous female rats. In both groups, protein expression of c-Fos (a neuronal activity marker) and calbindin (a location marker of the MPNc) were detected by fluorescent immunohistochemistry. The number of c-Fos-immunoreactive cells with or without FG labeling in the MPNc was also measured. The number of c-Fos-immunoreactive cells significantly increased following ejaculation. Approximately 10% of FG-labeled cells in ejaculation male rats were immunoreactive for c-Fos, and this percentage value wa...Continue Reading

References

Dec 1, 1989·Brain Research Bulletin·F H De JongeN E van de Poll
Sep 15, 1980·The Journal of Comparative Neurology·R A GorskiA M Southam
Feb 12, 1998·Proceedings of the National Academy of Sciences of the United States of America·R B SimerlyK S Korach
Jul 31, 2003·Genes, Brain, and Behavior·H Würbel
Nov 5, 2008·Brain : a Journal of Neurology·Alicia Garcia-Falgueras, Dick F Swaab
Jul 21, 2009·The International Journal of Social Psychiatry·Ioannis Paxinos, Anastasia Kalantzi-Azizi
Jul 2, 2010·The Journal of Comparative Neurology·Chitose Orikasa, Yasuo Sakuma
Jul 16, 2013·Progress in Neurobiology·Antonio Argiolas, Maria Rosaria Melis

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Citations

Oct 12, 2016·Endocrinology·Yadanar MoeShinji Tsukahara
Jun 14, 2019·Neuroscience and Biobehavioral Reviews·Morgan M Rogers-Carter, John P Christianson
May 11, 2021·Neuropharmacology·Walter FrancesconiJoanna Dabrowska

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