A neuropsychologically-based intervention with increased follow-up support for employed women with multiple sclerosis: a pilot randomized controlled trial.

Clinical Rehabilitation
Marnina B StimmelFrederick W Foley

Abstract

To evaluate feasibility and acceptability of a neuropsychologically-based vocational intervention with increased follow-up support for women with multiple sclerosis. Single-blinded parallel-group randomized controlled trial with 12-month follow-up. Tertiary-care multiple sclerosis center. Forty-nine employed women with multiple sclerosis meeting criteria on measures of cognitive dysfunction (Symbol Digit Modalities Test), fatigue (Fatigue Severity Scale), and/or depression (Beck Depression Inventory/Patient Health Questionnaire). Participants received either neuropsychological testing and phone feedback regarding findings and tailored recommendations (standard-care treatment), or testing, in-person feedback, and two calls from a care-coordinator (experimental treatment). Feasibility measures included enrollment and attrition rates, and compliance to recommendations at 12-months between groups. Acceptability was evaluated by participants' report of benefit from interventions. Secondary analyses included evaluation of symptom changes (cognition, fatigue, depression) from baseline to 12-months. Of 49 women meeting screening measure thresholds, 44 were randomized to treatment groups (attrition: standard-care = 8, experimental = 6),...Continue Reading

References

Apr 1, 1977·Perceptual and Motor Skills·D M Gronwall
Dec 12, 2002·Multiple Sclerosis : Clinical and Laboratory Research·P FlacheneckerK V Toyka
Apr 16, 2003·Archives of Internal Medicine·Ann S LarameePeter Callas
Feb 18, 2004·Archives of Physical Medicine and Rehabilitation·Kurt L JohnsonDagmar Amtmann
Mar 12, 2004·Journal of the International Neuropsychological Society : JINS·Dean C DelisJames Holdnack
Jun 15, 2006·Journal of Neurology·N TéllezX Montalban
Sep 20, 2006·Journal of the International Neuropsychological Society : JINS·Ralph H B BenedictBianca Weinstock-Guttman
Jun 7, 2008·Multiple Sclerosis : Clinical and Laboratory Research·M KochJ De Keyser
Aug 5, 2008·Journal of Neurology·Laura J JulianDavid C Mohr
Nov 1, 2008·Arthritis and Rheumatism·Diane LacailleJohn M Esdaile
Sep 19, 2009·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Maja HanssonOwe Bodlund
Nov 26, 2009·Autoimmunity Reviews·Ron Milo, Esther Kahana
Dec 23, 2011·Multiple Sclerosis : Clinical and Laboratory Research·D W LangdonR H B Benedict
Apr 4, 2012·Disability and Rehabilitation·Joanna SweetlandE Diane Playford
Jan 1, 1996·Work : a Journal of Prevention, Assessment, and Rehabilitation·N G LaroccaK Gregg
May 23, 2014·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J Van SchependomG Nagels
Jul 24, 2014·PloS One·Hanne Marie Bøe LundeLars Bø
Jan 15, 2015·Multiple Sclerosis : Clinical and Laboratory Research·Scott B PattenNathalie Jetté
Mar 3, 2015·Journal of the International Neuropsychological Society : JINS·Cynthia A HonanJennifer Batchelor
Jun 1, 2016·Journal of Rehabilitation Medicine·Sophie Fantoni-QuintonAriane Leroyer
Sep 8, 2016·Multiple Sclerosis : Clinical and Laboratory Research·Nina GryttenKjell Morten Myhr
Oct 11, 2017·Journal of the Neurological Sciences·Meghan BeierFrederick W Foley
Nov 9, 2017·The Clinical Neuropsychologist·Dana L RosadoNeil H Pliskin
May 3, 2019·International Journal of MS Care·Marnina StimmelFrederick W Foley
Oct 12, 2019·Multiple Sclerosis : Clinical and Laboratory Research·Alfredo DamascenoFernando Cendes

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