A new assisted hatching technique using a piezo-micromanipulator

Fertility and Sterility
T NakayamaT Mori

Abstract

To estimate the efficacy of a new assisted hatching technique using a piezo-micromanipulator to support embryonic implantation. Sibling spare embryos from human cycles of IVF were allocated to either a treated group for assisted hatching by a piezo-micromanipulator or a nontreated control group. The Infertility and IVF unit of the Kyoto University Hospital. Sixty-eight women undergoing conventional IVF treatment. One hundred ten spare 4- or 8-cell embryos from 68 patients undergoing IVF were treated with the new assisted hatching technique, and the results were compared with those obtained for 112 sibling embryos without the treatment. In the assisted hatching procedure, zona thinning combined with drilling was performed by the vibration of a microneedle produced by the piezo-micromanipulator unit. The rates of partial hatching and completely hatched blastocysts. The rates of hatching and of hatched blastocysts per total developing blastocysts were significantly higher in the treated group (86.7% and 33.3%, respectively) than in the control group (15.3% and 2.8%, respectively). These results demonstrate that the newly devised zona thinning and drilling technique using a piezo-micromanipulator is useful for assisted hatching.

References

Aug 1, 1991·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J Cohen
Mar 1, 1991·Molecular Reproduction and Development·X ZhangD T Armstrong
Mar 1, 1984·Journal of in Vitro Fertilization and Embryo Transfer : IVF·R G EdwardsJ M Webster
Apr 1, 1995·Biology of Reproduction·Y Kimura, R Yanagimachi
Apr 1, 1993·Journal of Assisted Reproduction and Genetics·M J TuckerG Wright

❮ Previous
Next ❯

Citations

Aug 11, 2004·Fertility and Sterility·David FrankfurterDavid Keefe
Oct 30, 2012·Ontogenez·I N RozhkovaS Ia Amstislavskiĭ
Sep 29, 2011·Fertility and Sterility·Po-Wei ChuGwo-Jang Wu
Feb 2, 2010·Reproductive Biomedicine Online·Mojtaba Rezazadeh ValojerdiBahar Movaghar
Apr 7, 2009·Gynécologie, obstétrique & fertilité·J Blessmann-RosetB Macé
Sep 5, 2013·Animal Science Journal = Nihon Chikusan Gakkaihō·Hidetoshi IshibashiKazuhiko Seki
Jul 14, 2004·IEEE Transactions on Bio-medical Engineering·Kerem Ediz, Nejat Olgac
Feb 11, 2009·IEEE Transactions on Nanobioscience·Youhua TanShuk Han Cheng
Aug 31, 2001·Human Reproduction·D A BlakeM Wikland
Jan 20, 2018·Journal of Assisted Reproduction and Genetics·Alessandra AlteriPatrizia Rubino
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Sarah-Kate CarneyLinsey Nelson
Feb 14, 2006·IEE Proceedings. Nanobiotechnology·K K Tan, S C Ng
Aug 3, 2005·Journal of Biomechanical Engineering·Kerem Ediz, Nejat Olgac
Jan 4, 2018·Systems Biology in Reproductive Medicine·Iman HalvaeiMohammad Ali Khalili
Mar 18, 2021·The Cochrane Database of Systematic Reviews·Lauren LaceyM Ahsan Akhtar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.