A new avenue to the synthesis of GAG-mimicking polymers highly promoting neural differentiation of embryonic stem cells

Chemical Communications : Chem Comm
Mengmeng WangHong Chen

Abstract

A new strategy for the fabrication of glycosaminoglycan (GAG) analogs was proposed by copolymerizing the sulfonated unit and the glyco unit, 'splitted' from the sulfated saccharide building blocks of GAGs. The synthetic polymers can promote cell proliferation and neural differentiation of embryonic stem cells with the effects even better than those of heparin.

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Citations

Apr 21, 2016·ACS Applied Materials & Interfaces·Yuqi YuanLin Yuan
Oct 16, 2016·Biomacromolecules·Samantha J PaluckHeather D Maynard
Jul 13, 2018·Macromolecular Rapid Communications·Pratik GurnaniSébastien Perrier
Feb 27, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mariana I NevesCristina C Barrias
Feb 15, 2017·Reviews in the Neurosciences·Elena A PozhilenkovaAlla B Salmina
Aug 28, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yuecheng CuiLin Yuan
Dec 14, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Qian LiChangyou Gao
Nov 2, 2017·Frontiers in Integrative Neuroscience·Chieh YuLarisa M Haupt
Sep 19, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Wei SunHong Chen
Mar 14, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhonglin LyuHong Chen
Dec 28, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Weifeng ZhaoChangsheng Zhao
Mar 30, 2021·ACS Biomaterials Science & Engineering·Sofia PeressottiRylie A Green
Apr 1, 2020·ACS Applied Materials & Interfaces·Sixuan ZhangHong Chen

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