PMID: 37226Mar 1, 1979

A new broad-spectrum aminoglycoside antibiotic complex, sporaricin. I. Fermentation, isolation and characterization

The Journal of Antibiotics
T DeushiT Oda

Abstract

Two new aminoglycoside antibiotics, sporaricins A (C17H35N5O5) and B (C15H32N4O4) produced by a rare actinomycetales, Saccharopolyspora hirsuta subsp. kobensis have been isolated by column chromatography on a cation-exchange resin. Sporaricin A is highly active against Gram-positive and Gram-negative bacteria including aminoglycoside-resistant strains.

Related Concepts

Aminoglycosides
Physicochemical Phenomena
Fermentation
Drug Stability
Hydrogen-Ion Concentration
Antibiotics

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