A new dimension for the human genome project: towards comprehensive expression maps

Nature Genetics
T StrachanJ S Beckmann

Abstract

The current Human Genome Project is largely devoted to structural characterisation of our genome. We now need international co-ordination of a second phase of genome analysis, the systematic construction of expression maps using both basic and high-resolution expression assays. Databases recording different types of expression pattern for a variety of human cell types need to be established and co-ordinated. There is a compelling need for a database of gene expression in early human development, but the scarcity of human material for study requires optimisation of research strategies and co-ordination of expression studies in early human and mouse development.

References

Jul 1, 1992·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·R BaldockD Davidson
Sep 1, 1995·Nature Genetics·J Burn, T Strachan
Oct 20, 1995·Science·V E VelculescuK W Kinzler
Aug 1, 1995·Nature Genetics·M S Boguski, G D Schuler
Sep 30, 1994·Science·M RingwaldD Davidson
Apr 26, 1996·The Journal of Biological Chemistry·I MailletJ Labarre
Feb 15, 1996·Nature·S G Oliver
May 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M Schena
Jul 9, 1996·Proceedings of the National Academy of Sciences of the United States of America·D WangF J Ayala
Mar 1, 1996·Electrophoresis·N G Anderson, N L Anderson
Oct 25, 1996·Science·G D SchulerT J Hudson
Oct 25, 1996·Science·A GoffeauS G Oliver
Oct 1, 1996·Proceedings of the National Academy of Sciences of the United States of America·M SchenaR W Davis
Oct 25, 1996·Science·E S Lander
Dec 1, 1996·Nature Genetics
Dec 18, 1996·Journal of the National Cancer Institute·B Kuska
Dec 18, 1996·Journal of the National Cancer Institute·N Nelson
Apr 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M D Adams
Jan 16, 1997·Nature·A Goffeau
Apr 1, 1997·Nature Genetics·S Fields
Jan 27, 1998·Seminars in Cell & Developmental Biology·D DavidsonR Baldock
Jun 1, 1996·Nature Biotechnology·W Bains
Nov 1, 1996·Nature Biotechnology·B T Chait
Dec 1, 1996·Nature Biotechnology·D J LockhartE L Brown

❮ Previous
Next ❯

Citations

Feb 9, 1999·Prenatal Diagnosis·E Pergament, M Fiddler
Feb 5, 2000·Journal of Neuroscience Research·C ColantuoniJ Pevsner
Sep 18, 1998·Molecular Reproduction and Development·A LaurentM Vidaud
Jun 1, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·B NalP Ferrier
Jan 28, 2004·Comptes rendus biologies·Orit ShmueliDoron Lancet
Aug 6, 2002·Journal of Communication Disorders·Steven D Gray, Susan L Thibeault
Aug 28, 1998·Trends in Biotechnology·P Colas, R Brent
Aug 15, 2002·Trends in Genetics : TIG·Edwin McConkey
Jul 3, 1999·Trends in Genetics : TIG·C R Scriver, P J Waters
Feb 27, 2001·Molecular and Cellular Endocrinology·W WangP J Hornsby
Aug 6, 1998·Early Human Development·P J BullenT Strachan
Feb 20, 1998·Current Opinion in Genetics & Development·S Rastan, L J Beeley
Jun 6, 2000·Neuromuscular Disorders : NMD·F FougerousseJ S Beckmann
May 2, 2002·Drug Discovery Today·Mark B Swindells, John P Overington
Aug 1, 1997·Current Opinion in Chemical Biology·D F VeberM Gowen
Jun 1, 1997·Nature Genetics
Oct 19, 1999·Genome Research·P S WhiteT C Matise
May 15, 2007·Plant Physiology·Richard Martin KrisDavid W Galbraith
Dec 24, 2005·Physiological Reviews·Michael Whitaker
Aug 14, 2002·American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice·K BüssowG Walter
Aug 19, 1997·Proceedings of the National Academy of Sciences of the United States of America·R P Erickson
Jul 8, 1998·Proceedings of the National Academy of Sciences of the United States of America·M MaoZ Chen
Aug 5, 1998·Current Opinion in Genetics & Development·J H Nadeau, P J Dunn
Apr 10, 1999·Seminars in Radiation Oncology·A Brahme
Aug 24, 1999·Journal of Occupational and Environmental Medicine·P A SchulteM J Colligan
Dec 28, 1999·Acta Oncologica·A Brahme
Dec 6, 2002·Nature·Alexandre ReymondAndrea Ballabio
Mar 15, 2006·Nature Reviews. Genetics·Stylianos E Antonarakis, Jacques S Beckmann
Jul 11, 1998·Clinical Genetics·M A van Steensel, R M Winter
Jul 17, 1999·Journal of Inherited Metabolic Disease·C R Scriver, P M Nowacki
Mar 21, 1998·Methods : a Companion to Methods in Enzymology·C H Warden, J S Fisler
Mar 21, 1998·Methods : a Companion to Methods in Enzymology·P M NolanM Bućan
May 18, 1999·Analytical Biochemistry·A LuekingG Walter

❮ Previous
Next ❯

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