PMID: 3754711May 1, 1986Paper

A new drug and current strategy in the treatment of acute non-lymphocytic leukemia in adults

Gan to kagaku ryoho. Cancer & chemotherapy
M Ogawa

Abstract

Among new drugs being studied currently, AMSA and mitoxantrone have shown significant usefulness against acute non-lymphocytic leukemia in adults. Remission induction therapy consisting of daunomycin and cytosine arabinoside has been commonly selected as the first line of treatment and the complete remission rate obtained has exceeded 70%. Postremission therapy consolidation has been judged to be necessary while the clinical roles of maintenance and intensification remain to be clarified and appear to still require an investigational approach.

Related Concepts

Related Feeds

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.

AML: Role of LSD1 by CRISPR (Keystone)

Find the latest rersearrch on the ability of CRISPR-Cas9 mutagenesis to profile the interactions between lysine-specific histone demethylase 1 (LSD1) and chemical inhibitors in the context of acute myeloid leukemia (AML) here.